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1、 2025 IEEE International Solid-State Circuits ConferenceISSCC 2025 Tutorial 8Intelligent Neural Interfaces:Fundamentals and Future DirectionsProf.Mahsa ShoaranEPFL,Switzerlandmahsa.shoaranepfl.chFebruary 16,20251 of 86Mahsa ShoaranISSCC T8 Intelligent Neural Interfaces:Fundamentals and Future Direct
2、ions 2025 IEEE International Solid-State Circuits ConferenceMahsa ShoaranISSCC T8 Intelligent Neural Interfaces:Fundamentals and Future DirectionsOutline2 of 86 Introduction and motivationsBasics of open-loop and closed-loop stimulationMajor trend:higher-channel-count systems Intelligent SoCs for sy
3、mptom control:seizure detectionRecent trends:Scalability,adaptability,and data efficiency Intelligent SoCs for brain-machine interfaces Conclusion and future directions Relevant papers in ISSCC 2025 2025 IEEE International Solid-State Circuits ConferencePrevalence of Major Brain DisordersMahsa Shoar
4、anISSCC T8 Intelligent Neural InterfacesSource:WHO3 of 86Over 1 in 3 people are affected by neurological conditions The leading cause of illness and disability worldwide Treatment resistance affects 2060%of psychiatric patients,30%in epilepsyUrgent need for effective treatment strategiesIncreasing i
5、nterest in neural interfaces and neuromodulation therapies 2025 IEEE International Solid-State Circuits ConferenceMahsa ShoaranIntroduction:Neural InterfacesTypes of neural signals:Non-invasive recordings:Electroencephalography(EEG)0.5100HzInvasive recordings:Action Potential or Spike 0.2510kHzElect
6、rocorticography(ECoG)1500HzLocal Field Potential(LFP)1500Hz4 of 86Depth Leads(LFP)Neural Interface ChipCortical Grids(ECoG)Microelectrodes(Spike)Bidirectional System:Sensing+Stimulation(neuromodulation)ScalpEEGISSCC T8 Intelligent Neural Interfaces:Fundamentals and Future Directions 2025 IEEE Intern