用于癌细胞分型和肿瘤纯度的分布式深度学习.pdf

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1、2024 Databricks Inc.All rights reservedRobert Kramer Robert Kramer Principal Data Scientist Principal Data Scientist-Providence HealthProvidence HealthJune 12 2024June 12 20241Distributed Distributed Cancer Cell Cancer Cell Typing&Typing&Tumor PurityTumor Purity2024 Databricks Inc.All rights reserve

2、dPrincipal Data Scientist Providence HealthDiverse academic background from aerospace engineering to systems&complexity scienceCurrent projects include predicting surgery admissions&molecular pathology ML/AI developmentRobert Kramer Robert Kramer-About Me About Me Me2024 Databricks Inc.All rights re

3、served122KCAREGIVERS38KNURSES34KPHYSICIANS$2.1BCOMMUNITY BENEFIT51HOSPITALS1000CLINICS29MTOTAL PATIENT VISITS2.6MCOVERED LIVES1700+PUBLISHED RESEARCH STUDIES1HEALTH PLAN18SUPPORTING HOUSING FACILITIESHIGH SCHOOL NURSING SCHOOLS&UNIVERSITYProvidence OverviewProvidence Overview32024 Databricks Inc.All

4、 rights reservedTumor Purity Tumor Purity=Consistency and Objectivity:Consistency and Objectivity:Traditional manual estimates of tumor purity are subjective and often inconsistent.Quality Control:Quality Control:Ensures accurate analysis of tumor samples.Relating Tumor Environment to Genetic Relati

5、ng Tumor Environment to Genetic Markers:Markers:Tumor purity is critical for understanding the tumor microenvironment,which is linked to genetic biomarkers and patient outcomes.Integrating AL/ML into HistologyIntegrating AL/ML into Histology4Cell typing is the first step to understand the tumor micr

6、oenvironmentCell typing is the first step to understand the tumor microenvironmentMazzarini M,Falchi M,Bani D,Migliaccio AR.Evolution and new frontiers of histology in bio-medical research.Microsc Res Tech.2021 Feb;84(2):217-237.doi:10.1002/jemt.23579.Epub 2020 Sep 11.PMID:32915487;PMCID:PMC8103384.