生物科技赋能焕发青春光彩：美容与糖生物学的碰撞.pdf

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1、Ruby ChenProduct Manager Bloomage BiotechnologyWhere Beauty and Glycobiology（）Collide 1Decoding the“Non-Energy”Skincare Secrets of Natural Sugars12Insights of Glycobiology in the Beauty Industry3Skincare Solutions Based on Natural Sugars4Future Outlook:Beauty Meets GlycobiologyCONTENTS201Decoding th

2、e“Non-Energy”Skincare Secrets of Natural Sugars3Rediscovering the Hidden Identity of Sugars(Glycans/Carbohydrates)(/)Glycan Information Code on the Cell SurfaceSugar(Carbohydrates)Glycobiology is the study of the structure,function and biology of carbohydrates(Sugar),also called glycans.What is Glyc

3、obiology?4The Central Dogma The Importance of Carbohydrates The role of carbohydrates as structural components is particularly important in the construction of complex multicellular organs and organisms,as Interactions between cells and between cells and their matrix are necessary.All cells and macr

4、omolecules carry dense and complex covalently bound glycans(sugar chains,also known as oligosaccharides or polysaccharides).Expanded Central Dogma 5GlycobiologyWHAT:The scientific study of the structure,chemistry,biosynthesis,and biological function of polysaccharides and their derivatives.WHEN:1988

5、WHO:Professor Dewick University of OxfordDefinition and Origin of Glycobiology Over 50%of proteins are modified by glycosylation The potential information content of polysaccharides exceeds the combined total of nucleic acids and proteins6Glycosylation is an important post-translational modification

6、 of proteins.It refers to the covalent binding of oligosaccharides to specific amino acid residues on proteins in the form of glycosidic bonds.This modification is widely present in living organisms and is mainly catalyzed by glycosyltransferases,which link sugar chains to protein molecules to form