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益生菌膳食补充剂对犬肠道发酵代谢物和微生物群影响的可重复性.pdf

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1、Repeatability of the effects of dietary supplementation of yeast probiotic on gut fermentative metabolites and microbiota in dogsSuchodolski JS1,Bastos TS2,Souza RB2,Felix AP2,Legendre H3,Adib Lesaux A31Texas A&M University,4474 TAMU|College Station,TX77843-44742Department of Animal Science,Federal

2、University of Paran,Curitiba,80035-050,Brazil3Phileo by Lesaffre,Marc en Baroeul,59700,France jsuchodolskicvm.tamu.eduJan Suchodolski I have the following disclosures*related to my presentation Employee:Gastrointestinal Laboratory,Texas A&M University Grants/Research Contracts:Purina PetCare Researc

3、h Excellence Fund,Royal Canin,AKC-CHF Consulting:Purina,Nutramax Laboratories,IDEXX Laboratories,Phileo Investments:none I will discuss results of clinical trial(s)for the following agents that are currently NOT approved for use in animals.*Disclosures include spouse and immediate family where relev

4、ant.HEALTHYCOLONCourtesy:Dr.Chi-Hsuan Sung,GI LAB,TAMUEpitheliumMucus layerLive microorganism(what we see as feces)Suchodolski JS-Assessing and Managing the Gut Microbiome in Canine and Feline Practice.In“Purina Institute-Canine and Feline Clinical Nutrition Handbook,2023 edition”Actisaf white book-

5、Phileo by Lesaffre(2023)Actisaf white book-Phileo by Lesaffre(2023)Objective To evaluate the repeatability of To evaluate the repeatability of the effect of yeast probiotic the effect of yeast probiotic Saccharomyces Saccharomyces cerevisiaecerevisiae on fermentative metabolites and gut microbiota c

6、omposition and on fermentative metabolites and gut microbiota composition and function in dogs undergoing abrupt dietary change.function in dogs undergoing abrupt dietary change.Design&Diet Animals:healthy adult Beagle dogs(1-5 years)Challenge type:abrupt nutritional diet transition from moderate to

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本文研究了酵母益生菌Saccharomyces cerevisiae对狗在饮食突变情况下肠道发酵代谢物和微生物组成的影响。关键点如下: 1. 研究设计:健康成年比格犬在从中蛋白、中纤维饮食突变为高蛋白、高纤维饮食时,分为两组,一组补充酵母益生菌Actisaf® Sc50 PET,持续28天。 2. 益生菌效果:补充益生菌显著降低了粪便的pH值、氨和某些生物胺,改善了粪便质量,并对肠道健康产生了积极影响。 3. 重复性:益生菌的摄入反应在3个月后再次进行实验时表现可重复,改善了菌群失调指数,调节了肠道微生物的组成和功能。 4. 数据统计:使用Minitab软件进行统计分析,发现益生菌组的粪便特性、免疫和微生物组有显著变化。 5. 安全性:日常补充酵母益生菌在健康犬中是安全且耐受良好的。 核心数据引用: - 益生菌剂量:0.12克/天(1x10^10 CFU/克) - 粪便特性改善:pH值、氨和生物胺显著降低 - 菌群失调指数改善:r=-0.707(p<0.0001) - 益生菌摄入反应可重复性:实验1和实验2的比较 结论提示益生菌在调节犬肠道健康方面的潜力,并建议在更广泛的犬群体和不同生命阶段或疾病模型中进一步验证这些结果。
"狗狗益生菌的神奇效果?" - "健康狗狗补充酵母益生菌后,有哪些显著变化?" "狗狗肠道健康的秘密?" - "如何通过酵母益生菌改善狗狗的肠道微生物群和代谢物?" "益生菌效果可持续吗?" - "益生菌对狗狗的长期影响有多可靠?三个月后的重复实验揭示了什么?"
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