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1、Considerations for supplementing omega-3s(n-3s)in companion animal dietsDr.Alex Rankovic PhDDr.Anna Kate Shoveller PhD,PASDepartment of Animal Biosciences,University of Guelph,Guelph,ON,Canada1.Understand the metabolism and physiological roles of n-3 and n-6 FA in dogs and cats2.Review current publi
2、shed recommendations for these FA and research investigating the n-6:n-3 ratio across life stages in dogs and cats3.Evaluate the environmental sustainability and practicality of different n-3 FA sources available to the pet food industry Learning ObjectivesImportance of fatsSource of Source of essen
3、tial fatty essential fatty acidsacidsHelp absorb Help absorb vitamins vitamins(A,D,E and K)(A,D,E and K)Concentrated Concentrated source of energysource of energyTaste and texture Taste and texture of foodof foodFats as a source of essential fatty acidsDogs and cats can synthesize many fatty acids f
4、rom:Bacterial synthesis Amino acids GlucoseBut cannotBut cannot:Synthesize n-6 and n-3 fatty acids Cannot convert between families(n-6 n-3)Essential fatty acidsn-3sn-6sLinoleic Acid(LA)Alpha Linolenic Acid(ALA)Arachidonic Acid(AA)Eicosapentaenoic Acid(EPA)Docosahexaenoic Acid(DHA)-6 desaturase-5 des
5、aturase-4 desaturasePro-inflammatory signaling moleculesAnti-inflammatory signaling moleculesLinoleic Acid(LA)Alpha Linolenic Acid(ALA)Arachidonic Acid(AA)Eicosapentaenoic Acid(EPA)Docosahexaenoic Acid(DHA)-6 desaturase-5 desaturase-4 desaturasePro-inflammatory signaling moleculesAnti-inflammatory s
6、ignaling moleculesEssential fatty acidsn-3sn-6sDietary sources of n-6 and n-3 fatty acidsn-3sn-6sLinoleic Acid(LA)Linoleic Acid(LA)Alpha Linolenic Acid(ALA)Alpha Linolenic Acid(ALA)Corn oil Soybean oil Sunflower oil Flaxseed oil Camelina oilDietary sources of n-6 and n-3 fatty acidsn-3sn-6sArachidon