利用增强诊断技术提升环境监测程序.pdf

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1、PIONEERINGDIAGNOSTICSJulien Defferrard Associate Director,Augmented Diagnostics,AmericasELEVATE YOUR ENVIRONMENTAL MONITORING PROGRAM WITH AUGMENTED DIAGNOSTICSB I O M R I E U XWHY ENVIRONMENTAL MONITORING?Management responseProduct MonitoringHACCP Controls(oPRP&CCP)In-ProcessMonitoringEnvironmental

2、 MonitoringHygienic Infrastructure&PersonnelCleaning&SanitationFactory zoning&segregationRaw material managementContinuousImprovementControlsVerificationDiagnosticsAugmented DiagnosticsB I O M R I E U XNeed:Do things right everydayCONNECTED ROUTINE TESTING SOLUTIONSEMP ECOSYSTEMNeed:Clear,actionable

3、 EMPEMP eLEARNING Need:Help solving the problemPATHOGEN MAPPING(GENOMICS)Need:Do better over timeADAPTIVE SAMPLING(PREDICTIVE MODEL)B I O M R I E U X4WHY DIGITALIZE EMP?Information available in real timeDetect problems earlier with trendingAutomated CAPATime and cost savingsBetter executionFaster ti

4、me to actionEnsure EM plan is executed as intendedStandardization across plants and employeesAudit readinessAutomated scheduling,CAPA,reportingFaster and easier employee trainingReduces labor,production down-time and water/chemicals usagePATHOGEN MAPPING(ROOT CAUSE ANALYSIS)B I O M R I E U XPATHOGEN

5、 MAPPING(Whole Genome Sequencing)EM ROOT CAUSE ANALYSIS TOOLSGENE-UP TYPER(Multiplex PCR)B I O M R I E U XUSE CASE:CRONOBACTER IN INFANT FORMULABasic hygiene3Medium hygieneHigh hygiene111111Cronobacter dublinensisCronobacter turicensisCronobacter turicensisCronobacter turicensisCronobacter sakazakii

6、2020-102020-112020-122021-01Cronobacter dublinensisCronobacter turicensisCronobacter sakazakiiCronobacter turicensisCronobacter turicensis2020-102020-112020-122021-01October sampleNovember sampleDecember sampleJanuary sample2 weeks of production capacity back(