酵母和酵母衍生物能帮助降低伴侣动物的致病压力吗？.pdf

1、Can yeast and yeast derivatives help reduce pathogenic pressure in companion animals?Dr Aleksandra Szopinska,Senior Innovation and NPD Manager,Livalta/AB AgriLet me introduce yeastResources:Jach et al.,2022;Sukhihasri et al.,2013,MOS Beta-1.3,1.6-glucan Saccharomyces cerevisiae is the most widely us

2、ed yeast species in pet food“Generally Recognized as Safe”(GRAS)status for food and feed applications Yeast cell can provide both nutritional and functional benefits Cell interior-nutrition Yeast cell wall-functional benefitsCell interiorAlternative proteinContains minerals and vitaminsNucleotidesPa

3、latability enhancerYeast cell wallBinding of pathogenic bacteriaImprovement of intestinal integrityEnhancer of immune functionPrebioticMycotoxin bindingRestrictive measures like the ban by the European Union(EU)of antibiotics as growth promoters for farm animalsProphylactic interventions:gut health

4、supporting solutions (e.g.based on yeast)can help reduce the use of antibioticsWhy is yeast important:it can support“gut health”and therefore be part of a strategy to reduce antimicrobial resistance*Marques et al.,2018;Gwenzi et al.,2021*Salmonella in animals and feed in Great Britain:2022(publishin

5、g.service.gov.uk),Salmonella in dogs became reportable through amendments to the Zoonoses Order in the UK in 2001Antimicrobial resistance:key risk for pets&humans Antimicrobial resistance(AMR)-one of the most important human and animal health risks worldwide Dogs&cats can become ill when infected wi

6、th bacteria,but are often asymptomatic carriers risk of transmission Pathogens in pets reported to harbour resistance to several antimicrobials*Most common salmonella strains in dogs in the UK(2022)*Need to reduce the use of antibioticsWhat is“gut health”and where do R&D activities focus to support