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1、011.1 02011.2 051.3 10022.1 15132.2 162.3 172.4 192.5 25033.1 32313.2 34044.1 48474.2 494.3 521582.593.614.6401CHAPTER行01021.1.1 30020003002000300200020222302031.1 1.1.2 031.1.3 041.1.4 1.1.5 脸色发黄影响肝脏健康代谢变差脱发第二天没精神怕猝死黑眼圈头、脸出油月经失调体检肝指标偏高血管问题影响肾脏健康将军肚不担心熬夜影响其他情绪暴躁9.87%9.78%7.59%8.15%11.45%8.58%6.65%8.

2、49%0.30%4.93%6.61%4.29%7.59%4.59%1.07%13.92%9.82%10.09%9.76%8.93%8.96%9.04%8.11%6.95%5.56%3.13%2.27%1.65%0.82%0.92%0.04%0.08%男性女性不同性别人群关注的健康问题侧重点不同图11-不同性别关注的健康问题相比之下，男性更担心肾脏健康、精气神、将军肚、肝指标等方面问题，女性则更关注脸色发黄、脱发、代谢变差等现象。051.2 1.2.1 30020003002000061.2.2 071.2.2.1 1.2.2.2 081.2.3.1 1.2.3 091.2.3.2 101.2.

3、3.3 1.3 NAFLD1.4 1 2023,43(4):248-252.2 Modeling NAFLD disease burden in China,France,Germany,Italy,Japan,Spain,United Kingdom,and United States for the period 20162030J.Journal of Hepatology 2018 vol.69 j 896904.3 The Global Burden of Liver Disease:The Major Impact of ChinaJ.Hepatology.2014 Decem-b

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5、non-parenchymal cell recruit-ment in the kidney.J Hepatol,2018,68(4):744-753.3 4 5 KONOPKAR J,BENZER S.Clock mutants of drosophila melano-gasterJ.Proc Natl Acad SciUS A,1971,68(9):2112-2116.6 JAMES A A,EWER J,REDDY P,et al.Embryonic expressionof the period clock gene in the central nervous system of

6、 drosophilamelanogasterJ.EMBO J,1986,5(9):2313-2320.7 Grimaldi B,Bellet MM,Katada S,Astarita G,Hirayama J,Amin RH,Granneman JG,Piomelli D,Leff T,Sassone-Corsi P.PER2 controls lipid metabolism by direct regulation of PPAR.Cell Metab 2010;12:509-520.8 Paschos GK,Ibrahim S,Song WL,Kunieda T,Grant G,Rey