用于精确健康的多模态生成人工智能.pdf

1、Multimodal Generative AI for Precision HealthHoifung PoonMicrosoft Health FuturesHoifung Poon,Microsoft Health FuturesTop 20 drugs80%non-respondersMedicine Today Is ImpreciseMedicine Today Is ImpreciseWasted1/3 health spending$1 Trillion/year2Hoifung Poon,Microsoft Health FuturesCancer:Immunotherapy

2、Cancer:ImmunotherapyKeytruda:immunotherapy blockbuster($25B,2023)FDA approved for many cancer indicationsBut only work for minority of patientsWanted:Complex biomarker for better stratificationWanted:Complex biomarker for better stratification3Hoifung Poon,Microsoft Health FuturesContinuous Learning

3、 Health SystemData ProducerProvider,EHR VendorInsight ConsumerPharma,Payor,Regulator4Hoifung Poon,Microsoft Health FuturesRealReal-World Evidence(RWE)World Evidence(RWE)RealReal-worldworld datadata(RWD)(RWD)are the data relating topatient health status and/or the delivery of healthcare routinely col

4、lected from a variety of sources.RealReal-worldworld evidenceevidence(RWE)(RWE)is the clinical evidenceregarding the usage and potential benefits or risksof a medical product derived from analysis of RWDPopulation-scale free lunch5Hoifung Poon,Microsoft Health FuturesMultimodal Patient JourneyMultim

5、odal Patient Journey6Hoifung Poon,Microsoft Health FuturesMultimodal Patient JourneyMultimodal Patient JourneyGrowing array of infoGrowing array of info-rich modalities rich modalities 7Hoifung Poon,Microsoft Health FuturesMultimodal Patient JourneyMultimodal Patient Journeyhttps:/ Poon,Microsoft He

6、alth Futures9Precision Health Is a Multimodal Generative ProblemPrecision Health Is a Multimodal Generative Problemf=DiseaseDiseaseProgressionProgressionTreatmentTreatmentResponseResponseHoifung Poon,Microsoft Health Futures10Precision Health Is a Multimodal Generative ProblemPrecision Health Is a M