生物化学家如何在大数据健康科学培训中成长.pdf

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1、How A Biochemist Grew in Big Data Health Science Training 5thNational Big Data Health Science ConferenceFebruary 3,2024|Columbia,SC Jie Li,Ph.D.Assistant Professor,Department of Chemistry and Biochemistry,USCOutline My Unique Experience as A“R25 Fellow”Significant OutcomesFuture PlansMy Background B

2、.S.,M.S.,andPh.D.inPharmaceuticalSciencesA biochemist aiming to convert microbial(especially human microbiota)genes into thecompoundstheyencodeforimprovinghuman healthMy“R25 Fellow”Application Process Five different information sourcesAccommodationsreceivedfromUSCBDHSCDeadline,mentorMy“R25 Fellow”Le

3、arning Process Monthly“R25 Fellow”MeetingUSC BDHSC Seminars/WorkshopsCourses taken online(Coursera etc.)MachineLearning,StatisticalAnalysisofMicrobiome DataLiterature exchanges with my mentorsMy“R25 Fellow”Mentoring Process My MentorsDr.Christopher Sutton(Department of Chemistryand Biochemistry,USC;

4、machine learning)Dr.Qi Wang(Department of Mathematics,USC;mathematical modeling,machine learning)One-on-one meetings with mentorsMy“R25 Fellow”Mentoring Process Attending mentors lab group meetingMy“R25 Fellow”Mentoring Process Planned a workshop for USC BDHSCintegrating mutual expertiseMy“R25 Fello

5、w”Significant OutcomesOne manuscript in preparationNIH R35 MIRA(awarded)“Accessingandexpandingnaturalproductschemicaldiversitybybig-dataanalysisandbiosynthetic investigation”One NIH R41 proposal submitted(pending)Future PlansInnovative research directionsDiscovery of functional metabolites produced

6、by human microbiota Differential Metabolites HealthDiseasesDiscovery of functional metabolites produced by human microbiota Differential Metabolites HealthDiseasesHealthDiseasesDifferential Biosynthetic EnzymesDiscovery of functional metabo