利用 AI 实现精准医疗的下一次飞跃.pdf

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1、Harnessing AI for Precision Medicines Next LeapDr.Puthen Veettil Jithesh FRSBAssociate Dean for Educationjveettilhbku.edu.qaWorld Summit AI 2024Predicting response to therapyGene expression signatures using machine learningJithesh PV,Allen W,Coyle V,Proutski I,Stevenson L,Fenning C,Stewart G,Longley

2、 D and Johnston P(2008)Comparative analysis of supervised classification methods in predicting response to chemotherapy in colorectal cancer patients.NCRI Cancer Conference 2008.NCRI,Birmingham Precision Medicine Early detection of individuals at risk of developing diseases,for improving preventive

3、measures Enabling precise diagnosis of patients,with the aim of providing appropriate therapy Predicting the prognosis and treatment response,to enhance efficacy and reduce adverse effects of treatment Development of novel therapeuticsBastaki K,Umlai UKI and Jithesh PV(2023)Personalized Medicine.In

4、Rahman M(Ed)Metabolomics A path towards personalized medicine,Elsevier Academic PressPrecision MedicineThe precise characterization of health states,disease states,and therapeutic options for affected individuals using multi-omics,imaging and phenotypic data,combined with medical history,social/beha

5、vioral determinants,and the environmental knowledgeBastaki K,Umlai UKI and Jithesh PV(2023)Personalized Medicine.In Rahman M(Ed)Metabolomics A path towards personalized medicine,Elsevier Academic PressDisease Risk PredictionHuang,Y.J.,Chen,C.H.,&Yang,H.C.(2024).AI-enhanced integration of genetic and

6、 medical imaging data for risk assessment of Type 2 diabetes.Nature Communications,15(1),4230.AI-based integration of genetic and medical imaging data for risk assessment of Type 2 DiabetesIdentifying facial phenotypes of genetic disorders using deep learning:DeepGestaltGurovich,Y.,Hanani,Y.,Bar,O.,