CONF-13-Hugh-OConnor.pdf

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1、Global Warmingof PCDsName:Hugh OConnor MSC BSC C Eng.Affiliation:TUdublin,School of Bio SciencesTUdublin1SLIDE TITLETUdublin2Sterilisation Historically Originated from:Steam sterilizers are derived from domestic food cookers steam digester invented in 1679 by Denis Papin1679(16471712)Chamberlain(185

2、11908),working with Louis Pasteur,was the first to use elevated pressure for sterilization purposes(1879)Little happened until world war II 1950 1970 research18/10/2023vdo3TUdublin3First vacuum assisted processes:faster and more reproducible processesNot clear who was the first to apply vacuum assis

3、ted processes16/02/2022vdo4TUdublin4The Technology is old but historically saved lives”Mornington emigration station,South Australia Cholera,Plague and Typhoid were that main pathogens Autoclave manufactured in 1917 TUdublin5Parametric release and PCDs Parametric release is a system of release that

4、gives the assurance that the product has achieved the intended quality(STERILE)A Process Challenge Device(PCD)is a test device intended to provide a challenge to the sterilization process that is equal to or greater than the challenge posed by the most difficult item routinely processed.In other wor

5、ds,a PCD is used to confirm that a sterilizer has effectively sterilized ALL items processed in that cycle?TUdublin616/02/2022vdo7 Not clear who was the first to apply vacuum assisted processes Reason to apply vacuum:Time Reproducibility of processes Sterilized devices less time to elevated temperat

6、uresHistory of Vacuum assisted SterilisersTUdublin7Sterilisation conditions establishedCurrent times are first specified in:Precht JCH.Tempertur und Leben.Springer Verlag,Berlin,1955.Perkins JJ.Principles and Methods of Sterilization.Charles C Thomas,Springfield(IL),1956.16/02/2022vdo11Time minTempe