1605_Sharp.pdf

1、Which RDN Device?Prof Andrew SP Sharp MD Professor of Cardiology,University College Dublin and Mater Misericordiae Hospital,Dublin,IrelandDOI Consultant to Medtronic,Recor Medical,Boston Scientific,Penumbra,Angiodynamics,PhilipsHow do the devices work?How do the Devices work?Gel modelsReality of abl

2、ations in tissueSharp et al,JoH,2022Sakakura et al Eurointervention,2015Do we denervate enough?RF RDN IVY techniqueMahfoud F et al.J Am Coll Cardiol.2015;66:1766-75Device Efficacy Sham RCTsDevice efficacy real world data with RF RDNMahfoud,PCR,2021-23.5-16.4-17.6-11.6-15.9-18.4-14.3-21.5P 150 mmHg,3

3、 anti-hypertensive medicationsCKD definedas eGFR 3mm and move proximally towards the ostium.uRDN procedureMultiple renal arteries found in 30%of cadavers Accessory arteries are innervated and found in 30%of cadavers Different renal arterial sizes can be treated with single SPYRAL device Different re

4、nal arterial sizes require multiple balloons with uRDN1.Garcia-Touchard A,et al.TCT Connect,2020.Cost effectiveness Highly cost effectiveSharp et al,EHJ-QCCO 2023Conclusion Two devices approved Both have excellent efficacy and safety data Different volumes and duration of follow-up Different procedural characteristicsWhich RDN Device?Prof Andrew SP Sharp MD Professor of Cardiology,University College Dublin and Mater Misericordiae Hospital,Dublin,Ireland