1、As filed with the U.S.Securities and Exchange Commission under theSecurities Actof1933,asamended,on July 18,2025.Registration No.333-_UNITED STATESSECURITIES AND EXCHANGE COMMISSIONWashington,D.C.20549_FORM S-1REGISTRATION STATEMENTUNDERTHE SECURITIES ACT OF 1933_Drugs Made In America AcquisitionII

2、Corp.(Exact name of registrant as specified in its charter)_Cayman Islands 6770 98-1815624(Stateorotherjurisdictionofincorporationororganization)(PrimaryStandardIndustrialClassificationCodeNumber)(I.R.S.EmployerIdentificationNumber)Lynn StockwellChief Executive Officer and Executive ChairDrugs Made

3、In America AcquisitionII Corp.1 East Broward Boulevard,Suite 700Fort Lauderdale,FL33301(954)870-3099(Address,including zip code,and telephone number,including area code,ofregistrants principal executive offices)_Copies to:Mitchell S.Nussbaum,Esq.G.Alex Weniger-Araujo,Esq.Loeb&Loeb LLP345 Park Avenue

4、NewYork,NY10154Tel:(212)407-4000 Douglas S.Ellenoff,Esq.Stuart Neuhauser,Esq.Anthony Ain,Esq.Ellenoff Grossman&Schole LLP1345 Avenue of the AmericasNewYork,NY10105(212)370-1300_Approximate date of commencement of proposed sale to the public:As soon as practicable after the effectivedate of this regi

5、stration statement.If any of the securities being registered on this Form are to be offered on a delayed or continuous basispursuant to Rule415 under the Securities Actof1933 check the following box:If this Form is filed to register additional securities for an offering pursuant to Rule462(b)under t

6、heSecurities Act,please check the following box and list the Securities Act registration statement number of theearlier effective registration statement for the same offering.If this Form is a post-effective amendment filed pursuant to Rule462(c)under the Securities Act,check thefollowing box and li