张改平-超级疫苗理论假说与研究实践.pdf

1、超超级级疫疫苗苗Superior vaccine-理理论论假假说说与与研研究究实实践践-Theoretical hypotheses and research practice张张改改平平Zhang Gaiping2024年年4月月26日日 龙龙湖湖现现代代免免疫疫实实验验室室LonghuLaboratory一带一路国际生猪产业大会为为什什么么Why?我我们们已已经经有有很很多多疫疫苗苗，已已经经解解决决了了许许多多问问题题。We already have a lot of vaccines that have solved a lot of problems.但但许许多多问问题题仍仍然然没没

2、有有得得到到解解决决。However,many problems remain unresolved.人人类类流流感感疫疫苗苗是是一一个个典典型型例例子子。The human influenza vaccine is a typical example.不不够够高高效效、不不够够广广谱谱、不不够够安安全全、浪浪费费生生理理潜潜力力。Not efficient enough,not broad-spectrum enough,not safe enough,waste physiological potential.一带一路国际生猪产业大会什什么么是是What?我我们们为为了了解解决决这这些些现

3、现实实问问题题提提出出了了超超级级疫疫苗苗的的理理论论概概念念和和研研究究路路径径。In order to solve these practical problems,we put forward the theoretical concept and research path of Superior vaccine.所所谓谓超超级级就就是是实实现现更更高高效效和和更更广广谱谱保保护护。The so-called super is to achieve more efficient and broader spectrum protection.超超级级疫疫苗苗还还要要更更加加安安全全并并

4、节节约约生生理理潜潜力力。Super vaccines are also safer and save physiological potential.显显然然，需需要要用用新新技技术术途途径径来来解解决决。Clearly,new technological approaches are needed.一带一路国际生猪产业大会分分类类Classification超超级级高高效效Super efficient超超级级广广谱谱Super Broad Spectrum满满足足安安全全与与节节省省生生理理潜潜力力的的新新要要求求Meets new requirements for safety and

5、 physiological sparing potential一带一路国际生猪产业大会怎怎么么实实现现How to achieve精精确确：精精确确结结构构设设计计=精精确确免免疫疫启启动动Precise:Precise structure design=precise immune priming微微量量：纳纳克克级级免免疫疫保保护护Trace:nanogram level of immune protection纯纯化化：减减轻轻副副作作用用，降降低低生生理理消消耗耗Purification:Reduce side effects and physiological consumptio

6、n一带一路国际生猪产业大会怎怎么么实实现现How to achieve超超级级高高效效：重重构构主主抗抗原原Super Efficient:Reconstruct the main antigen超超级级广广谱谱：重重构构保保守守的的共共同同抗抗原原，多多聚聚主主抗抗原原Super broad spectrum:reconstitution of conserved common antigens,multiple main antigens一带一路国际生猪产业大会研研究究实实践践Research practice技技术术基基础础Technical Basis超超级级疫疫苗苗研研究究实实践践S