欧洲工业高性能计算资源：需求与机遇.pdf

1、HPC in Pharmaceutical IndustryEuropean Industrial HPC Resources:Needs&OpportunityAndrea R.BeccariVice President EXSCALATE,Dompe Farmaceutici spA*Pharma R&D Effectiveness Clinical Development Failure Rate 90%Treatment Efficacy 4%-60%1.1 Trillion Euro Market*Evolution of MedicinePersonalizedPrecisionP

2、redictivePreventiveModernIdentify patients at risk of developing a disease,thereby enabling either prevention or early treatment of that diseasedisease treatment that considers individual variability in genes,environment,and lifestyle for each personTraditionalInformationInterpretationPrediction(Cli

3、nical)Trial&ErrorPatients in clinical trialsReal World PatientsWhole PopulationStatisticsQualitative ModellingQuantitative ModellingHorizon funding accelerates the development of Exscalate201520162017201820192020202120222023202420252026202720286X Vs Benchmark500X*Vs Benchmark6500X Vs BenchmarkBenchm

4、ark:Supercomputer-Based Ensemble Docking Drug Discovery Pipeline with Application to Covid-19-2020 SUMMIT supercomputer +IBM+NVIDIA 1st Patent Quantum computing Molecular DockingCloud Version on EU HPC CentersSOFTWAREUnlock AI potentiality for EU(Pharma Industry)DATAHARDWAREAre we constructing the n

5、ecessary frameworks to facilitate FAIR principles in healthcare data management?FAIR(findable accessible interoperable and reusable)Are we organizing semiconductor investments to boost the EUs competitive edge?Are we investing sufficiently in High-Performance Computing(HPC)centers to meet the needs

6、of industrial applications?Should open-source software be a prerequisite for obtaining industrial grants?Are we nurturing public-private partnerships within the EU to propel the development of generative AI architectures and targeted training programs?Is a single EU framework being established for t