1、2015 Annual ReportA Plant Biotechnology Company with an Important Mission:To Reduce the Harm Caused by Smoking22nd Century Group,Inc.Dear Fellow Shareholders:The year 2015 was a transformative year for our Company and the year 2016 will be a time of even greater opportunity for 22nd Century.In 2015,
2、our Company expanded our already dominant intellectual property portfolio and attracted the interest and?BRAND A”Very Low Nicotine cigarettes that contain approximately 95%less nicotine than conventional cigarette brands.The New England Journal of Medicine?N Engl J Med 2015;373:1340-1349?22nd Centur
3、ys proprietary SPECTRUM research cigarettes.Funded by the FDA and the National Institute on Drug Abuse,a division of?our SPECTRUM Very Low Nicotine cigarettes consumed far fewer?cigarettes with conventional nicotine content.Simultaneous to these important milestones,22nd Century began to?Our revenue
4、s increased from less than$530,000 in 2014 to more than$8.5 million in 2015.Indeed,our revenues in 2015 exceeded prior?rolling out MAGIC Very Low Nicotine cigarettes in Europe beyond?for continued success and growth.As discussed in earnings calls over the last year,22nd Centurys enormous potential i
5、n the near term and the long term rests with?industries.With ownership or exclusive control of more than 200 issued patents and more than 50 pending patent applications around the world,22nd Century has a virtual monopoly on the genes in the tobacco plant responsible for nicotine production.Ours is
6、the only company in the world capable of growing tobacco with 95%less nicotine than conventional plants and,at the other end of the spectrum,no other company can grow cigarette tobacco with nicotine content as high as our proprietary plants.This technology and the incredibly important independent cl