1、A new era of precision The unprecedented impact of generative AIIntroductionPrecision medicine(PM),a paradigm-shifting model in healthcare and life sciences,is focused on delivering tailored treatments and prevention strategies to individual patients.As this important clinical discipline continues t

2、o evolve,artificial intelligence(AI),and more specifically generative AI,will likely serve as the cornerstone of innovation and accelerator of progress.The use of AI in patient risk assessments,screening,and diagnosis are showing the most progress to date.However,AI-driven treatment decisions are wh

3、ere we see the most opportunity.Healthcare providers and ancillary technical experts(e.g.,data scientists,machine learning engineers,etc.)can use AI to analyze complex data patterns,determine optimal patient treatment paradigms,anticipate treatment responses,and deliver personalized healthcare exper

4、iences.On the operational front,AIs potential to enhance research-based and clinically based healthcare operations is significant.However,there are challenges that need to be addressed,including ensuring data privacy,managing ethical implications,obtaining regulatory approvals,and securing infrastru

5、cture investments.Further,there is a need to foster trust among healthcare professionals and patients regarding AIs reliability and transparency,which will require robust validation studies.This paper delves into AIs current role across the PM landscape.We address the challenges impeding broader ado

6、ption and provide insights into potential AI-driven solutions based on emerging learning models through illustrative case studies.Federated learning,in particular,will play a pivotal role in constructing a robust,scalable,and privacy-preserving PM ecosystem.2 2023 KPMG LLP,a Delaware limited liabili