CONF-10-Hannah-Siwe.pdf

1、Evaluation of a UV-C LED device for disinfection of medical instrumentsHannah SiweLaboratory of Liver Infectious Diseases,Faculty of Medicine and Health Sciences,Ghent University,Ghent,BelgiumResearch and Development,ZAPARAY,Lokeren,Belgium1OVERVIEWINTRODUCTION Ultraviolet radiation(UVR)and backgrou

2、nd UVR sources/UVR damage Hospital acquired infection(HAI)and infection prevention and control measures Reprocessing and challengesOBJECTIVESMETHODS Instrument assessment Workflow UV testingRESULTS Results on the standard surface(petri dish)and medical devices CONCLUSION23INTRODUCTIONSource:adapted

3、from Norcast weatherULTRAVIOLET RADIATION(UVR)ENERGY10200280315400Source:adapted from Browne,K.,Brought to Light:How Ultraviolet Disinfection Can Prevent the Nosocomial Transmission of COVID-19 and Other Infectious DiseasesINTRODUCTION%absorbedUV-CUV-BUV-A510095UV-CUV-BUV-AVacuumUVINITIAL UV DISCOVE

4、RYDISCOVERY OF MUTAGENIC PROPERTIES OF UVUSE OF UV FOR TREATMENT OF TB*Thomas BluntArthur Downes18771801Niels FinsenJohann Ritter1895*tuberculosis4BACKGROUND5UVR DAMAGELIPIDSPROTEINSDNARNAAgingSunburnSkin cancerCataractConjunctivitisBlindnessCELULLAR LEVELFigure made in BioRenderMACROSCOPIC LEVELUVR

5、 SOURCESTRADITIONAL UV MERCURY LAMPSLIGHT EMITTING DIODESEXCIMER LAMPSHeat generationmercurywavelength controllcompactlimited output intensitywavelength controllbroad spectrumlcostRelatively new technologydifferent sizesdifferent sizesozone7HOSPITAL ACQUIRED INFECTION(HAI)AND INFECTION PREVENTION AN

6、D CONTROL MEASURESSource:adapted from European Centre for Disease Prevention and Control(2016/2017)INFECTION PREVENTIONAND CONTROL MEASURES 4.9 log10 CFU/mLCOMPLETE REDUCTION 6.8 log10 CFU/mLPARTIAL REDUCTION 2 log10 CFU/mL(HINGE)NO REDUCTION(HOLLOW CAVITIES)COMPLETE REDUCTION 9 log10 CFU/mLSTANDARD