1、伪狂犬案例分析及检测评估伪狂犬案例分析及检测评估PRV case analysis and test evaluation 耿健耿健 Jian Geng2023年年3月月 Mar.2023大纲大纲 Outlines一、一、背景背景 Background二、材料和方法二、材料和方法 Materials and Methods三、结果与分析三、结果与分析 Results and Analysis四四、结论、结论 Conclusion五五、致谢、致谢 Acknowledgement一、背景Background 猪场发病背景信息猪场发病背景信息 Background of the Case 猪场拥有4
2、条生产线,1个公猪舍,共5000头母猪和67公猪;公猪舍为单独区域;Pig farm has 4 production lines and 1 boar barn,with a total of 5000 sows and 67 boars;The boar house is a separate area 本场原来为伪狂犬阳性场,20年7月份引入伪狂犬阴性后备母猪,生产成绩稳定。This field was originally a pseudorabies-positive field.In Jul.20,2000 pseudorabies-negative gilts were intr
3、oduced,and the production results were stable.临床症状临床症状 Clinical signs2020年12月22日,2线配怀舍开始出现流产。Dec.22nd.20,sows were aborted began in gestation house of 2nd production line.2021月1月15日,2线出生的猪只开始出现神经症状。Jan.15th.21,Newborn piglets in the second production line after birth started to exhibit neurological
4、symptoms.怀疑可能感染了伪狂犬;PRV infection was suspected.2021年1月18日,4线配怀舍开始出现流产,23日,分娩舍仔猪出现神经症状Jan.18th.21,the phenomenon that sows were aborted began to occur in gestation house of 4th production line,and on the 23rd,the piglets in the farrowing house showed neurological symptoms.2021年2月2日-6日,1线和3线陆续出现了相似的症
5、状。Feb.2-6.21,similar symptoms appeared in 1st and 3rd production line.仔猪使用抗生素治疗无效;No response to antibiotic treatment.主要剖检病变:脑膜充血,肺脏出血。Primary necropsy lesions:meningeal hyperemia,pulmonary congestion 临床症状临床症状 Clinical signs流产 abortion 死胎 still born 弱仔 weak piglet 脑膜充血meningeal hyperemia 肺脏出血pulmona
6、ry congestion 流行病学流行病学 Epidemiology从1月1日开始,截止3月28日,共计流产167头母猪。流产高峰集中在2月2日到2月26日,共24天;167 sows were aborted from Jan 1st to Mar 28th and peaked at from Feb 2nd to Feb 26th,a total 24 days;流行病学流行病学 Epidemiology从1月1日开始,截止3月28日,共计死亡2000余头仔猪,仔猪死亡高峰集中在1月23日到2月28日,与流产高峰基本重合;A total of more than 2,000 pigle