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1、SPECIAL REPORTThe Race Is On:ESG in the Pharma Industry SPECIAL REPORT2“Pharmaceutical firms are on their ESG game.They get the notion of science-based targets.Theyunderstand the criticality of delivering on ESG.”Director of ESG,large pharma company,US3L.E.K.ConsultingSPECIAL REPORTThe Race Is On:ES
2、G in the Pharma IndustryContents1.Summary 42.Introduction 63.L.E.K.survey 74.Summary of results 95.Climate commitments heating up?126.Strategies for future-proofing 214L.E.K.ConsultingSPECIAL REPORTThe Race Is On:ESG in the Pharma IndustrySummaryPerformance on ESG(environmental,social and governance
3、)metrics is becoming an increasingly important consideration for stakeholders across the corporate ecosystem,and the pharmaceutical industry is no exception.Events like COP bring mainstream attention to the topic,increasing the importance of addressing these urgent issues.In this report we look at t
4、he ESG priorities of pharma companies and their relative maturity across the different dimensions of ESG,based on an L.E.K.survey of 49 pharma businesses.Our findings highlight the following:.4ESG is gaining momentum.According to a Bloomberg Research forecast,ESG assets will surpass$50 trillion by 2
5、025,and pharma is going beyond legal requirements to address ESG-related issues.1Pharma companies appear comparatively more mature on the social dimensions of ESG.This is no surprise given the industrys fundamental purpose of improving the health of society.With the importance of health equity comin
6、g to the forefront,the emphasis on social metrics is set to continue,with topics like access and affordability of key concern for pharma.In addition,complex and expensive treatments coming to market will mean patients and healthcare systems will need more support throughout the treatment journey.Lar
7、ge companies are more mature in terms of ESG policies,initiatives and metrics than small companies.The level of transformation needed to embed ESG in an established business may be overwhelming;however,it provides an opportunity to drive innovation,optimise business processes and reduce costs in the
8、 medium to long term.In the coming years big pharma will have to design a functional and corporate level approach that means their net-zero and other ESG commitments become realistic.23SPECIAL REPORTThe Race Is On:ESG in the Pharma Industry5L.E.K.ConsultingSmall companies,whilst less mature on ESG m
9、etrics,are in a unique position to embed sustainability into their growth strategies.This will not only mean they are well prepared for increasing ESG regulation,but also provide significant competitive advantage as healthcare customers increasingly value sustainable products.Small biotech and pharm
10、a companies must answer a very different question from their more mature peers:“Where do we start?”4There is increasing pressure felt by the wider pharma supply chain,with contract manufacturing organisations(CMOs)rating as more mature in their ESG policies than their customers.Both small biotechs t
11、hat rely heavily on service providers and big pharmas that have an overwhelming challenge to address huge Scope 3 emissions will depend on assistance from their suppliers.There is a need for action;however,exactly what that action looks like will differ from company to company.Materiality assessment
12、s are a sensible starting point on this journey,but most respondents have highlighted their progress on this is nascent.This represents an opportunity to set a priority course to mature ESG in pharma.56SPECIAL REPORTThe Race Is On:ESG in the Pharma IndustryIntroductionThe ESG movement,fuelled by glo
13、bal concerns regarding climate change and wealth,health and social inequality,aims to measure and manage the impact that organisations have on their ecosystem and extends well beyond environmental footprint.Approaches to measuring ESG performance in a standardised way are still emerging,and the scal
14、e and diversity of demands as well as the lack of uniform measurement methods are posing challenges.Nonetheless,the pressure on businesses is growing:having ESG policies and clear targets in place and demonstrating progress towards these are becoming an essential part of business strategy.Attitudes
15、towards and performance on ESG vary widely between company sizes and regions,and thus,ESG has been a means of competitive differentiation for forward-thinking companies.Growing stakeholder expectations are establishing ESG as a prerequisite for success,particularly for attracting investment.The Unit
16、ed Nations Principles for Responsible Investing,founded in 2006 and committed to the inclusion of ESG-based analysis in investment decision-making,has grown to managing more than$120 trillion.Bloomberg Research forecasts that ESG assets will exceed$50 trillion by 2025,representing over a third of gl
17、obal assets under management.The global pharma and biotech industry is no exception in fact the imperative to forward the ESG agenda is even more urgent.Health leaders around the world are hailing climate change as the biggest health threat facing humanity,with disproportionate impacts across the wo
18、rld due to social inequality.Because they are organisations centred on improving human health,ESG is fundamental to pharma and biotech.The healthcare sector that the industry serves is also under pressure,being responsible for 4%of global greenhouse gas emissions.Many national programmes like Greene
19、r NHS are working hard to decarbonise the sector and will increasingly value products and services with reduced environmental footprints.The demand for ESG in the industry is clear;however,the solutions are complex and wide ranging,from low-impact manufacturing,circular packaging and responsible was
20、te management to initiatives driving equitable access and affordability.Pharmas increased commitment to ESG goals has,in turn,put pressure on other players along the value chain.As a result,CMOs and contract development and manufacturing organisations(CDMOs)have taken steps to advance their ESG poli
21、cies to keep pace with their customers.L.E.K.Consulting6SPECIAL REPORTThe Race Is On:ESG in the Pharma IndustryL.E.K.surveyThe survey conducted by L.E.K.Consulting in 2022 has shown that pharma companies and CMOs/CDMOs are developing advanced policies to manage ESG performance,clearly exceeding lega
22、l requirements.L.E.K.asked 49 pharmaceutical/biotech firms and 22 CMOs in the US,Europe and Asia how far along they were in setting goals and developing and implementing policies across 42 metrics within the E,S and G dimensions.Respondents were dedicated ESG managers or senior management in operati
23、onal functions with ESG responsibility(e.g.heads of manufacturing,chief operating officers)and represented companies in different annual revenue categories ranging from$10million to over$10 billion(see Figure 1).Figure 1 Survey respondents by industry segment and size L.E.K.Consulting7Number of resp
24、ondents$10 million$500 million$1 billion$10 billionOver$10 billionPharma/biotech CMO Source:L.E.K.survey and analysis100203040502049222181210SPECIAL REPORTThe Race Is On:ESG in the Pharma IndustryRespondents were asked to rate their companys maturity on each ESG metric,capturing the existence and de
25、gree of implementation of policies exceeding the minimum legal requirements in their region(see Figure 2).Figure 2 Metrics and rating scale per metric L.E.K.Consulting8Less advancedMore advanced12345 Antimicrobial resistance management Biodiversity impact management Customer information re:environme
26、ntal impact Energy efficiency GHG*emissions Non-GHG environmentally damaging emissions Non-water resource use Solid waste management Supply chain environmental standards Water resource use Wastewater management Affordable access to drugs in LMIC Availability of drugs in LMIC Community development Ex
27、ternal representation Freedom to join unions Health and safety Human rights Internal representation and equity Non-discriminatory work environment Non-salary-related benefits Pay(minimum wage and overtime)Pharmacovigilance Product quality policies R&D focus on rare diseases Social criteria for selec
28、ting suppliers Supply chain continuity mechanisms Animal testing and ethics Anti-corruption policies Clear ESG roles,divisions and capabilities Data collection Data security ESG accountability ESG materiality assessment ESG monitoring and performance review ESG risk management Executive pay linkage
29、to ESG objectives Healthcare professional engagement policies Internal ESG communications Patient engagement policies Policies for engaging with suppliers Whistleblowing and escalation mechanismsEnvironmentalSocialGovernanceSource:L.E.K.survey and analysisNote:GHG=greenhouse gas;LMIC=low-and middle-
30、income countriesESG metricsRating scale per metricMeets legal requirements,if anyIn the process of defining policies,initiatives or targets that exceed legal requirements,if anyFully defined but not implemented policies,initiatives or targets that exceed legal requirements,if anyFully defined and pa
31、rtially implemented policies,initiatives or targets that exceed legal requirements,if anyFully implemented policies,initiatives or targets that exceed legal requirements,if anySPECIAL REPORTThe Race Is On:ESG in the Pharma IndustrySummary of resultsDoubling down on ESG:surpassing legal requirements
32、The L.E.K.survey found that on all three dimensions E,S and G the mean response exceeded a rating of 3(out of 5),meaning that the average organisation has defined policies that go beyond legal requirements.However,the level of implementation varies by company size,ESG dimension and region(see Figure
33、 3).Figure 3 Level of progress on E,S and G metrics average rating across all pharma/biotech respondents Social policies are leading the way Social policies and initiatives aim to address how companies interact with their stakeholders:employees,investors,consumers and local communities.Aspects consi
34、dered here are diverse and include both internal policies which protect the well-being of employees within an organisation and external facing ones which aim to ensure equitable access to medicines by patients.The internally facing policies such as pay and non-discriminatory work environments are ta
35、ble stakes for large organisations;however,our survey showed that many small organisations are behind in ensuring these are consistently implemented.L.E.K.Consulting9All-company mean1 23 4 5 Source:L.E.K.survey and analysisGovernanceSocialEnvironmentalLess advancedMore advanced3.133.523.39SPECIAL RE
36、PORTThe Race Is On:ESG in the Pharma IndustryExternal activity driving social value for patients and society includes R&D for rare diseases,improving availability of drugs in low-and middle-income countries and affordable access.These issues have been at the core of pharmas strategies for a long tim
37、e,and therefore the skew towards social policy has been well documented.This prioritisation of patient-focused ESG initiatives is set to continue,as challenges around equal access and affordability are exacerbated by the economic downturn and more expensive complex therapies(see Figure 4).Figure 4 L
38、evel of progress on social metrics by company size all pharma/biotech respondentsL.E.K.Consulting10All-company meanNote:LMIC=low-and middle-income countries Source:L.E.K.survey and analysis$10 million$500 million$1 billion$10 billionOver$10 billion1 23 4 5 Human rightsHealth and safetyNon-salary-rel
39、ated benefitsInternal representationand equityNon-discriminatorywork environmentFreedom tojoin unionsPay(minimum wageand overtime)Social criteria forselecting suppliersR&D focus onrare diseasesCommunity developmentExternal representationPharmacovigilanceAvailability ofdrugs in LMICsProduct quality p
40、oliciesAffordable access todrugs in LMICsSupply chaincontinuity mechanismsLess advancedMore advancedInternal metricsExternal metricsHuman rights considerations such as child labour,trafficking and slavery form the most mature internal metric within the social dimension,and pharma companies of all si
41、zes have implemented strict policies along their value chain and across global operations.Respondents to our survey reported social criteria for selecting suppliers and R&D for rare diseases as the most mature external metrics:Pharma companies have a sharp focus on their supply chain across all ESG
42、dimensions,including the social category;improving suppliers ESG performance can be an effective way to reduce pharmas own footprint.All survey participants stated that they had partially or fully implemented social criteria for selecting suppliers.Developing innovative therapies for orphan diseases
43、 has long been a core pharma strategy.Substantial unmet needs,limited competition and high pricing potential have attracted R&D interest.In addition,favourable legislation through dedicated and accelerated regulatory pathways,tax benefits,and subsidies provide further incentives in many regions.SPEC
44、IAL REPORTThe Race Is On:ESG in the Pharma IndustryL.E.K.Consulting11“Rare disease R&D is a priority because it makes a lot of sense commercially,as well as making a positive impact.A lot of manufacturers are moving into rare indications.The majority of the high burden conditions have a lot of compe
45、tition,so pharma companies look to rarer diseases.”Director of health economics and outcomes,small-to-medium sized pharma,UK SPECIAL REPORTThe Race Is On:ESG in the Pharma IndustryClimate commitments heating up?Environmental standards in the pharma supply chain are the most mature environmental metr
46、ic.L.E.K.s survey found that pharmas policy development and implementation were the least mature on the environmental dimension(see Figure 5).The industry has made some progress on this metric,but some pharma experts still feel that there is a gap between environmental policies and the other compone
47、nts of ESG.Figure 5 Level of progress on environmental metrics by company size all pharma/biotech respondentsEnvironmental standards in the pharma supply chain are the most mature environmental metric,followed by water resource use and solid waste management in pharmas own operations:The supply chai
48、n is a key area of focus for pharma companies across all ESG dimensions,including environmental.Many firms have committed to ambitious environmental targets and within these are focusing their attention on Scope 3 emissions,which account for the majority of pharmas emissions.L.E.K.Consulting12All-co
49、mpany mean1 23 4 5 Note:GHG=greenhouse gasSource:L.E.K.survey and analysisSupply chainenvironmental standardsWater resource useSolid waste managementBiodiversity impactmanagementGHG emissionsNon-GHG enviromentallydamaging emissionsEnergy efficiencyWastewater managementNon-water resource useCustomer
50、informationre:environmental impactAntimicrobialresistance managementLess advancedMore advanced$10 million$500 million$1 billion$10 billionOver$10 billion3.593.533.433.373.163.083.083.002.862.692.67SPECIAL REPORTThe Race Is On:ESG in the Pharma Industry Optimisation of water resource use is driven by
51、 a range of factors,including minimising the risk to future operations by reducing reliance on scarce resources as well as saving on utility expenses.Pharmaceutical waste covers waste generated in the extraction and refining of constituent reagents,discarded or expired medications,and product packag
52、ing.A significant bulk of solid waste is hazardous to humans and the environment.Organisations which can minimise their impact in this area lessen the risk of punitive action as well as reputational harm as a result of environmental damage.Opportunities exist for pharma and biotech to find innovativ
53、e solutions to reduce waste in traditionally challenging areas,for example by introducing circularity for primary packaging.TerraCycle,a US recycling company,has set up a global initiative to recycle empty blister packs in collaboration with pharmaceutical companies and community pharmacies.Organisa
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