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医药行业文章摘要标题梳理:2023年ASCO本土创新药进展跟踪-230503(25页).pdf

上传人: 好*** 编号:124541 2023-05-05 25页 2.27MB

1、丁丹(分析师)邮箱:电话:0755-23976735证书编号:S0880514030001黄炎(分析师)电话:021-38675923证书编号:S088052107000122023年ASCO本土创新药进展跟踪0102ASCO(ASCO)2023 ASCO2023.6.2-2023.6.6ASCO2022ASCODESTINY-Breast04EnhertuHer2ADCHK2021.4.1-2021.6.3031%2022.5.13-2022.7.638%2023 ASCO4ASCOOralPoster DisscusionPosterPblication OnlyBDASCOVXfWsWl

2、YjZnPtRrM8ObPbRsQnNoMsRiNrRnQeRpPsPaQrRuMNZmPqOxNmOqQ32023年ASCO本土创新药进展跟踪2023 ASCOHER2CDK4/6Publication OnlyNeoadjuvant pyrotinib plus trastuzumab,dalpiciclib,and letrozole for triple-positive breast cancer:A pilot trial.Pilot Trial+https:/meetings.asco.org/abstracts-presentations/224842Publication O

3、nlyPreliminary analysis of pyrotiniband dalpiciclib-based therapy in HER2-positive advanced breast cancer(ABC).HER2https:/meetings.asco.org/abstracts-presentations/222842Poster SessionUpdated results from a phase 2 study on dalpiciclib and pyrotinib,a dual-oral chemotherapy-free regimen in HER2-posi

4、tive advanced breast cancer(DAP-HER-01).IIHER2(DAP-HER-01)https:/meetings.asco.org/abstracts-presentations/222583Poster SessionPLEASURABLE:Results and biomarkers analysis from the phase II study of dalpiciclib combined with pyrotiniband endocrine therapy(ET)in women with dual-receptor positive(ER+/H

5、ER2+)metastatic breast cancer(MBC).PLEASURABLE(II)ER+/HER2+https:/meetings.asco.org/abstracts-presentations/222584CDK4/6Publication OnlyNeoadjuvant stereotactic body radiotherapy plus dalpiciclib and exemestane for hormone receptor-positive,HER2-negative breast cancer.HR+/HER2-https:/meetings.asco.o

6、rg/abstracts-presentations/2248432023 ASCOPD(L)142023年ASCO本土创新药进展跟踪2023 ASCOPD(L)1SHR-1701PD-L1/TGF-Poster SessionSHR-1701 in combination with platinum-based chemotherapy and BP102(a bevacizumab biosimilar)for persistent,recurrent,or metastatic cervical cancer:Data from a phase 1b/3 study.SHR-1701BP

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本文主要介绍了2023年ASCO会议中本土创新药的进展情况。其中包括了多种药物的临床试验结果,如HER2 ADC药物Enhertu、CDK4/6抑制剂pyrotinib和dalpiciclib、PD-L1/TGF-β抑制剂SHR-1701、Famitinib、BTK抑制剂Zanubrutinib、BGB-11417、Zanidatamab、Ociperlimab、Sintilimab、PD-1/CTLA-4双特异性抗体AK104、PD-1/VEGF双特异性抗体AK112、PD-1单抗Toripalimab、PD-1/CTLA-4双特异性抗体Tifcemalimab、HER-2 ADC药物RC48、TROP2 ADC药物SKB264、RET抑制剂KL590586、BCMA CAR-T细胞疗法Cilta-cel、PD-1/CTLA-4双特异性抗体QL1706、CDK4/6抑制剂trilaciclib、VEGFR抑制剂Fruquintinib、EGFR抑制剂Icotinib、Furmonertinib、EGFR/HER3 ADC药物BL-B01D1、EGFR/HER3双特异性抗体SI-B001、PD-1/CTLA-4双特异性抗体SI-B003、CD19/CD3/PD-L1/4-1BB四特异性抗体GNC-038、JAK1抑制剂Golidocitinib、EGFR exon20抑制剂Sunvozertinib、MetAP2抑制剂APL-1202、KRAS G12C抑制剂D-1553、AR抑制剂Deutenzalutamide、RET抑制剂SY-5007、ALK抑制剂SY-3505、KRAS G12C抑制剂ZG19018、JAK1/2/3抑制剂Jaktinib等。这些药物的临床试验结果表明,它们在治疗各种癌症方面具有潜在的疗效和安全性。
2023年ASCO本土创新药进展如何? 哪些药物在乳腺癌治疗中取得进展? 2023年ASCO有哪些值得关注的本土创新药物?
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