Hartwick_aging eye diseases.pdf

1、Introduction toAging Eye DiseasesAndrew Hartwick,OD,PhDAge-Related Eye Diseases Cataracts Glaucoma Diabetic Retinopathy Macular DegenerationMature cataract examplehttps:/www.aao.org/CataractCow lens(untreated)Cow lens(induced cataract)Hartwick&Sivak,2003Cataracthttps:/ surgery is the most common sur

2、gery performed in the worldOver 3 million cataract surgeries performed in the USA each yearAnatomy of the Eye The retina is a thin(1/2 mm thick)piece of tissue that lines the back of the eye Can be considered an outgrowth of the brainAnatomy of the RetinaThe retina is a multi-layered structurePhotor

3、eceptors in outer retina capture light(using their photopigment)and convert it electrical signal Retinal ganglion cells are output neurons send the signals to brainDyer&Cepko,2001Ritchey et al.,2010The Optic Nerve Head Location where the axons of the retinal ganglion cells leave the eye to travel ba

4、ck to the brain Meshwork of small pores that the axons go through called the lamina cribosaQuigley et al,Arch Ophthalmol 1990Age-Related Eye Diseases Cataracts Glaucoma Diabetic Retinopathy Macular DegenerationIf pressure inside eye gets too high,the lamina cribosa can bow outwards,resulting in dama

5、ge to RGC axons travelling through optic nerve headInner Retina Blood Supply Inner retina receives blood supply from retinal blood vessels Branch off carotid artery and enter eye at optic nerve head(blind spot)Left image is retina as viewed by a clinician looking through pupil of eye with an ophthal

6、moscope Window on blood vessel function(HTN,high cholesterol,diabetes)Webvision.med.utah.eduAge-Related Eye Diseases Cataracts Glaucoma Diabetic Retinopathy Macular DegenerationDiabetes can cause damage to blood vessels,resulting in leaks Macula Fovea is part