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APRL参与IgA类别转换
APRL参与IgA类别转换
行业数据
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医药行业IgA肾病专题：潜在需求庞大耐赋康放量确定性高-240918（71页）.pdf
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2025-09-28
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国内IgA肾病新药竞争格局
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竞争格局
2025-09-28
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全球及中国IgA肾病治疗药物市场预计将快速增长（单位：亿美元）
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行业数据
2025-09-26
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Povetacicept针对IgA肾病全球3期试验设
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行业数据
2025-09-24
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除了IgA肾病，同类TACI资产已在SLE、MG等适应症上取得POC数据
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行业数据
2025-06-12
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2024版KDIGO指南（公开审查草案）：IgA肾病治疗策略与用药方案
fCDogr7lip/og73oobDnq63nmoTpqbHliqjlm6DntKAgfCDmsrvnlpfnm67moIcgfCDkuLTluoror5XpqozmiqXlkYrmnInmlYjnmoTlubLpooTmjqrmlr3vvIjpgILnlKjkuo7kurrnvqTvvIkgfCDkuI3lkIzlnLDmlrnnmoTkuLTluorlrp7ot7UgfAp8IC0tLSB8IC0tLSB8IC0tLSB8IC0tLSB8CnwgfCDlh4/lsJHoh7Tnl4XmgKdJZ0HvvIhHZC1JZ0Ex77yJ5ZKMSWdB5YWN55ar5aSN5ZCI54mp55qE5b2i5oiQ77yI5a+55Zug5rK755aX77yJIHwgfCDlkJfmm7/puqbogIPphZrpha8gfAp8IHwg5YeP5bCR5a+86Ie06IK+5Y2V5L2N5Lii5aSx55qE54m55byC5oCn6amx5Yqo5Zug57SgIHwgfCDnjq/lraLntKAgfAp8IHwg5YeP5bCR6IK+5bCP55CD54KO55eHIHwgfCDlsYDpg6jkvZPliIfpmaTmnK8gfAp8IHwg5YWo6Lqr57OW55qu6LSo5r+A57SgIHwgfCAgfAp8IHwg5o6n5Yi26KGA5Y6LIHwg5pS55Y+Y55Sf5rS75pa55byPIHwgIHwKfCB8IOmZjeS9juiCvuWwj+eQg+mrmOa7pOi/h+eOh+WSjOibi+eZveWwv+WvueiCvuWwj+eQg+mXtOi0qOeahOW9seWTjSB8IOiCvue0oC3ooYDnrqHntKflvKDntKDns7vnu5/mipHliLbliYLvvIhSQVNp77yJIHwgIHwKfCB8IOmZjeS9juW/g+ihgOeuoemjjumZqSB8IOmSoOiRoeiQhOezluWFsei9rOi/kOibi+eZvTLmipHliLbliYLvvIhTR0xUMmnvvIkgfCAgfAp8IHwgfCDlj7jluJXlnablnaYgfCAgfAoK6LWE5paZ5p2l5rqQ77ya44CKMjAyNCBLRElHTyBJZ0FO5oyH5Y2X5b6B5rGC5oSP6KeB56i/44CL77yM5pa55q2j6K+B5Yi456CU56m25omA
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行业数据
2025-05-26
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图25全球及中国IgA肾病治疗药物市场规模（2016-2030E）
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市场规模
2024-06-21
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表9全球进入III期及以上阶段的IgA肾病创新药
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其它
2024-06-21
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图表34IgA肾病的竞争格局
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有研究表明APRIL 在 GALT 中表达，APRIL-TACI 与 IgA 类别转换有关。在对正常人体肠道组织的检查中发现，APRIL在 GALT、固有层和肠上皮中表达，在靠近淋巴组织的区域表达特别强烈。据推测，APRIL 有助于维持黏膜屏障并促进黏膜浆细胞的存活。此外 ，APRIL/BAFF-TACI已被证明在体外可以诱导IgA 类别转换，但是只有APRIL 在体内可能具有这种作用。
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医药行业IgA肾病专题：潜在需求庞大耐赋康放量确定性高-240918（71页）.pdf
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