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图表36LNP技术专利溯源情况
图表36LNP技术专利溯源情况
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所属报告：
医药生物行业创新药研发专题系列：小核酸药物从上游解决疾病-211125（45页）.pdf
打包全文图表
相关数据
图37mRNA-LNP疫苗相关良症状分类
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行业数据
2026-03-16
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图34各类组织靶向LNP发占比
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行业数据
2026-03-16
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Alnylam的脂质纳米颗粒（LNP）递送系统
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行业数据
2025-09-28
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Alnylam的脂质纳米颗粒（LNP）递送系统
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行业数据
2025-09-28
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蓬勃生物mRNA-LNP技术平台：包封率和颗粒表征
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行业数据
2023-06-12
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LNP各组分的比例
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行业数据
2022-11-15
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LNP各组分的比例
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行业数据
2022-11-15
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四种RNA产品LNP组分对比
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行业数据
2022-08-01
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LNP作为递送载体的mRNA制剂结构示意
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行业数据
2022-08-01
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不同公司LNP组分的构成
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行业数据
2022-05-17
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lnP、SiC、GaN等材料的特性参数对比
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行业数据
2022-04-08
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LNP递送技术的专利授权情况
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行业数据
2022-02-21
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全球部分LNP技术专利交易情况
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行业数据
2021-12-30
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目前LNP技术的专利格局
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行业数据
2021-12-30
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最新数据
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2026-07-30
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2026-07-30
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行业数据
2026-07-30
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为进一步提高安全性，第三代脂质主要是增强其水解速度。例如 L319采用了一种在体内容易被酯酶降解的伯酯取代烷基链中的两个双键之一，其代谢物为β氧化途径中脂肪酸的潜在基质，具有较好的安全性，并且能够迅速通过肝脏被排泄，在肝脏中的半衰期不到一小时，因此相比第二代具有更好的耐受性和安全性，目前在 BioNTech和 CureVac产品中被使用。此外，通过使用其他可离子化脂类取代 MC3也可以提高安全性和效价，例如 Moderna开发了一类新的可电离脂质 SM-102来替代MC3，提高效率。
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医药生物行业创新药研发专题系列：小核酸药物从上游解决疾病-211125（45页）.pdf
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图表7目前已上市的小核酸药物情况
图表6小核酸药物可以类比20年前的抗体行业情况
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