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国内市场主要的HER2TKI在研情况
国内市场主要的HER2TKI在研情况
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所属报告：
创新药行业系列深度报告（二）：肿瘤治疗黄金赛道-221124（94页）.pdf
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市场规模
2026-07-14
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fCDlubTku70gfCDplIDllK7pop3vvIjkur/lhYPvvIkgfCB5b3nvvIgl77yJIHwKfC0tLS0tLXwtLS0tLS0tLS0tLS0tLS0tfC0tLS0tLS0tLS18CnwgMjAyMCB8IDEuNiAgICAgICAgICAgIHwgLSAgICAgICAgfAp8IDIwMjEgfCAyLjIgICAgICAgICAgICB8IDM5ICAgICAgIHwKfCAyMDIyIHwgMy4xICAgICAgICAgICAgfCA0MyAgICAgICB8CnwgMjAyMyB8IDIuOCAgICAgICAgICAgIHwgLTkgICAgICAgfAp8IDIwMjQgfCA4LjUgICAgICAgICAgICB8IDIwMCAgICAgIHwKCui1hOaWmeadpea6kO+8muaRqeeGteWMu+iNr++8jOilv+mDqOivgeWIuOeglOWPkeS4reW/gw==
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2026-07-14
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体结合。当HER-2 与配体结合后，通常通过受体二聚化及胞质内酪氨酸激酶区的自身磷酸化，激活酪氨酸激酶的活性，从而激活下游信号通路，包括：RAS/RAF/MAPK途径、PI3K/AKT 途径、信号转导及转录激活（STAT）途径等。在乳腺癌、胃癌等肿瘤中，常常会发现HER-2 的过表达，因此HER2成为一个有潜力的治疗靶点。
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创新药行业系列深度报告（二）：肿瘤治疗黄金赛道-221124（94页）.pdf
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