1、UNITED STATESSECURITIES AND EXCHANGE COMMISSIONWashington,D.C.20549 FORM 40-F(Check One)Registration statement pursuant to Section 12 of the Securities Exchange Act of 1934 or X Annual report pursuant to Section 13(a)or 15(d)of the Securities Exchange Act of 1934 For the fiscal year ended December 3
2、1,2017 Commission file number 001-32001Aptose Biosciences Inc.(Exact name of registrant as specified in its charter)Canada(Province or other jurisdiction of incorporation ororganization)2836(Primary Standard IndustrialClassification Code Number(if applicable)98-1136802(I.R.S.EmployerIdentification N
3、umber(if Applicable)5955 Airport Road,Suite#228Mississauga,Ontario L4V 1R9Canada(647)479-9829(Address and Telephone Number of Registrants Principal Executive Offices)Aptose Biosciences U.S.Inc.12770 High Bluff Drive,Suite 120San Diego,California 92130(858)926-2730(Name,Address(Including Zip Code)and
4、 Telephone Number(Including Area Code)of Agent For Service in the United States)Securities registered or to be registered pursuant to Section 12(b)of the Act.Title of each classCommon Shares,no par valueName of each exchange on which registeredThe NASDAQ Capital Market Securities registered or to be
5、 registered pursuant to Section 12(g)of the Act.None Securities for which there is a reporting obligation pursuant to Section 15(d)of the Act.None For annual reports,indicate by check mark the information filed with this Form:X Annual Information FormX Audited Annual Financial Statements Indicate th
6、e number of outstanding shares of each of the issuers classes of capital or common stock as of the close of the period covered by the annual report:27,502,053 Indicate by check mark whether the Registrant by filing the information contained in this Form is also thereby furnishing the information to