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SNIA-SDC23-GuilhermeDaCostaMartins-Pantheon-DNA-Data-Storage-CODEC_1.pdf

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1、#|2023 SNIA.All Rights Reserved.Virtual ConferenceSeptember 28-29,2021Pantheon DNA Data Storage CODECExperiences,Challenges,and InnovationsAndr Guilherme da Costa Martins,PhD Biomed.Sci.Bioinformatics researcher Institute for Technological Research-IPT,Brazil andremartinsipt.br Who are we?The Instit

2、ute for Technological Research-IPT has been contributing actively for 124 years to science and technical advances.We provide technical solutions for industry,governments,and society,enabling them to overcome the challenges of our time.1|2021 Storage Developer Conference.IPT-Lenovo.All Rights Reserve

3、d.ATGCTAGCAAGGCGTGCAATGCTAGCAAGGCGTGCAOriginalBinary dataEncoded DNAStoraged DNA moleculesSequenced DNARecoveredBinary dataDNASequencingDNASynthesisENCODINGDECODING2|2023 SNIA.All Rights Reserved.A versatile CODEC:Robust DNA data architecture Binary data pre-processing Multiple choices for mapping a

4、lgorithms Multi-layer ECC strategy Supports SNIAs sectors(S0&S1)Includes NGS processing algorithms Compatible with multiple sequencing and storage strategiesThe Pantheon CODEC3|2023 SNIA.All Rights Reserved.ApolloArtemisC hironHermesHephaestusG aia4|2023 SNIA.All Rights Reserved.5|2023 SNIA.All Righ

5、ts Reserved.6|2023 SNIA.All Rights Reserved.Apollo,the encoding moduleApollo and the Muses-Michel Dorigny,early 1640s7|2023 SNIA.All Rights Reserved.5-3EndPrimerStartPrimerAddresslabelPayloadInner ECCAdenineGuanineThymineCytosineApollo:oligonucleotide structure8|2023 SNIA.All Rights Reserved.ATTGCAT

6、GGATAACGAnalysis&Processing5-3EndPrimerStartPrimerAddresslabelPayloadInner ECCAdenineGuanineThymineCytosineMetadata from file system9|2023 SNIA.All Rights Reserved.Apollo:encoding process(.)Metadata fromfile systemCodec parameters from data blocksMetadata fromdata blocks(.)10|2023 SNIA.All Rights Re

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本文介绍了一种名为Pantheon CODEC的DNA数据存储编码解码器,由多个模块组成,包括Apollo编码模块、Chiron NGS预处理模块、Hermes地址导向模块和Artemis解码模块。Apollo模块支持多种序列读取和存储策略,Chiron用于预处理NGS读取,Hermes优化地址库搜索和匹配,Artemis负责解码和错误校正。文中提供了实验数据,表明使用Pantheon CODEC能够在序列读取和合成过程中有效恢复数据,即使在低覆盖率和高缺失率的情况下也能保持高数据完整性。此外,文中还讨论了Pantheon CODEC在不同 sequencing platforms和library preparation策略下的模拟效果,以及Gaia模块在开发过程中的作用。
"DNA数据存储创新技术" "如何实现高效DNA数据解码?" "探索未来DNA数据存储前景"
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