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使用注射用索玛鲁肽治疗肥胖症患者的特征、态度和体验:OUTSTEP 1 研究的中期分析.pdf

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1、Vallis M et al.Presented at the 33rdEuropean Congress on Obesity(ECO),1215 May 2026,Istanbul,Trkiye.Characteristics,attitudes and experiences of individuals using injectable semaglutide for obesity management:An interim analysis of the OUTSTEP 1 studyMichael Vallis,Salah Abusnana,Jennifer L.Baker,An

2、dreea Ciudin,Leyla Hernandez Donoso,Sandra Elia,Dmitry Estulin,Bruno Halpern,Samantha Hocking,Hyuk-Sang Kwon,Susanne Reger-Tan,Ricardo Reynoso,Hanen Samouda,Arya M.Sharma,on behalf of the OUTSTEP Study GroupAssociao Brasileira para o Estudo da Obesidade e Sndrome Metablica(ABESO),So Paulo,Brazil,and

3、 Obesity Center,Hospital 9 de Julho,So Paulo,BrazilThis study was sponsored by Novo Nordisk A/S and is registered with ClinicalTrials.gov(NCT07154238).Medical writing support was provided by Isabella Goldsbrough Alves,PhD,of Apollo,OPEN Health Communications,and funded by Novo Nordisk A/S,in accorda

4、nce with Good Publication Practice(GPP)guidelines(ismpp.org/gpp-2022).Scan QR code or visit the web site below for the oral presentation slides:https:/ M et al.Presented at the 33rd European Congress on Obesity(ECO),1215 May 2026,Istanbul,Trkiye.Vallis M et al.Presented at the 33rd European Congress

5、 on Obesity(ECO),1215 May 2026,Istanbul,Trkiye.Disclosures Bruno Halpern has received funding as a speaker or advisory board consultant from:AstraZeneca Boehringer Ingelheim Currax Pharmaceuticals Daiichi Sankyo Eli Lilly Novartis Novo NordiskVallis M et al.Presented at the 33rd European Congress on

6、 Obesity(ECO),1215 May 2026,Istanbul,Trkiye.IntroductionThe aim of the OUTSTEP 1 study was to capture comprehensive insights into the experience,expectations and satisfaction level of patients using injectable semaglutide in the real worldUnderstanding real-world patient needs,expectations and attit

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1. **研究目的**:OUTSTEP 1研究旨在真实世界评估使用注射用司美格鲁肽(semaglutide)肥胖管理患者的体验、期望与满意度(NCT07154238)。 2. **患者特征**: interim分析纳入389例患者(德国、澳大利亚),79%存在合并症(如2型糖尿病37%、高血压37%、抑郁24%),基线BMI中位数35kg/m²。 3. **核心期望与满意度**: - 78%患者对整体治疗满意(7分量表5-7分); - 主要期望为减重(75%)、食欲控制(81%)及生活质量(QoL)改善(84%)。 4. **生活方式管理**:83%患者认为用药后更易维持健康饮食和运动;52%药物由基层医疗(PCP/GP)处方。 5. **支持工具**:91%患者知晓至少一种体重管理工具(如运动追踪器、饮食管理APP),44%曾接受营养师指导。
**减肥效果如何?** **用药体验满意吗?** **生活方式改变容易吗?**
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