1、Investor Update F.Hoffmann-La Roche Ltd 4070 Basel Switzerland Investor Relations email: Phone+41 61 688 88 80 1/14 Ad hoc announcement pursuant to Art.53 LR Basel,29 January 2026 Roche reports strong 2025 results with 7%sales growth Group sales grew by 7%1 at constant exchange rates(CER;2%in CHF),d
2、riven by strong demand for medicines and diagnostic solutions.Sales in the fourth quarter increased by 8%,reflecting the positive momentum.Pharmaceuticals Division sales increased by 9%(3%in CHF),with Phesgo(breast cancer),Xolair(food allergies),Ocrevus(multiple sclerosis),Hemlibra(haemophilia A)and
3、 Vabysmo(severe eye diseases)being the top growth drivers.Diagnostics Division sales grew 2%(-3%in CHF)as demand for pathology and molecular solutions continued to more than offset the impact of healthcare pricing reforms in China.Core operating profit increased by 13%(5%in CHF),driven by higher sal
4、es and efficiency gains.Core earnings per share showed growth of 11%(4%in CHF);IFRS net income increased by 58%(50%in CHF),due to the strong operational performance in 2025 and the base effect of impairment charges in 2024.Highlights:US and EU approval for the subcutaneous form of Lunsumio for a typ
5、e of blood cancer EU approval for Gazyva/Gazyvaro for lupus nephritis,a serious kidney disease Positive data on several therapies:(phase III)giredestrant for breast cancer,fenebrutinib for two forms of multiple sclerosis,Gazyva/Gazyvaro for two immune-related diseases,PiaSky for a rare,life-threaten
6、ing kidney condition and Enspryng for a rare autoimmune disease that affects the brain,spinal cord and optic nerves;(phase II)CT-388 for obesity Advancement of 10 key molecules into phase III development in 2025 EU CE mark for novel Elecsys Dengue Ag test to diagnose dengue and for cobas BV/CV assay