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Dianthus Therapeutics-2026-JPM.pdf

上传人: 明**** 编号:1069718 2026-01-17 29页 2.53MB

1、Advancing a leading autoimmune-focused companyJanuary 12,2026 2Forward-looking statementsCertain statements in this presentation,other than purely historical information,may constitute“forward-looking statements”within the meaning of the federal securities laws,including for purposes of the safe har

2、bor provisions under the United States Private Securities Litigation Reform Act of 1995,express or implied statements regarding future plans and prospects,including statements regarding the expectations or plans for discovery,preclinical studies,clinical trials and research and development programs,

3、in particular with respect to claseprubart and DNTH212,and any developments or results in connection therewith,including the target product profile and administration of claseprubart and DNTH212;the anticipated timing of the initiation and results from those studies and trials;expectations regarding

4、 the clinical trial designs or indications;expectations regarding the time period over which the Companys capital resources are expected to be sufficient to fund its anticipated operations;and expectations regarding market size,patient population size,and potential opportunities for complement thera

5、pies,in particular with respect to claseprubart and DNTH212.Claseprubart and DNTH212 are investigational agents that are not approved as therapies in any indication in any jurisdiction worldwide.The words“opportunity,”“potential,”“milestones,”“runway,”“will,”“anticipate,”“achieve,”“near-term,”“catal

6、ysts,”“pursue,”“pipeline,”“believe,”“continue,”“could,”“estimate,”“expect,”“intend,”“may,”“might,”“plan,”“possible,”“predict,”“project,”“should,”“strive,”“would,”“aim,”“target,”“commit,”and similar expressions(including the negatives of these terms or variations of them)generally identify forward-lo

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1. 公司推进两款自身免疫疗法:claseprubart(aC1s单抗)和DNTH212(BDCA2/BAFF/APRIL双功能融合蛋白),均处于临床阶段,目标为同类最佳。 2. 核心数据:现金约5.14亿美元,资金储备可支撑至2028年;claseprubart半衰期约8周,DNTH212潜在Q4W或更低频率皮下注射。 3. 2026年里程碑:claseprubart启动gMG III期试验、CIDP II期中期分析(Q2’26)、MMN II期顶线数据(2H’26);DNTH212更新适应症优先级(1H’26)及I期健康志愿者顶线数据(2H’26)。 4. 市场潜力:claseprubart瞄准美国>10万gMG、>4万CIDP及>1万MMN患者;DNTH212跨多个自身免疫疾病,潜在同类最佳疗效与便利性。
新药疗效如何? 自身免疫疗法进展? 临床试验有何突破?
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