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Ascentage Corporate Presentation_Vfinal jpm.pdf

上传人: 明**** 编号:1069699 2026-01-17 43页 2.82MB

1、Dajun Yang,M.D.,Ph.D.Chairman&CEOJanuary 14,2026AAPG.NASDAQ|6855.HKEXCorporate Presentation44th AscentageJ.P.Morgan Healthcare ConferenceCautionary Note Regarding Forward-Looking Statements2This presentation has been prepared by Ascentage Pharma Group International(the“Company”)and includes forward-

2、looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 and Section 27A of the Securities Act of 1933,as amended,and Section 21E of the Securities Exchange Act of 1934,as amended.All statements,other than statements of historical facts,contained in this presenta

3、tion may be forward-looking statements,including statements that express the Companys opinions,expectations,beliefs,plans,objectives,assumptions or projections regarding future events or future results of operations or financial condition.These forward-looking statements are subject to a number of r

4、isks and uncertainties that may cause actual results,levels of activity,performance or achievements to be materially different from the information expressed or implied by these forward-looking statements.For factors that could cause actual results to differ materially from the forward-looking state

5、ments in this presentation,please see the sections titled“Risk factors”and“Special note regarding forward-looking statements and industry data”in the Companys Form 20-F filed with the SEC on April 16,2025,and other filings with the SEC that the Company made or makes from time to time,and with respec

6、t to non-U.S.investors only,the sections headed“Forward-looking Statements”and“Risk Factors”in the prospectus of the Company for its Hong Kong initial public offering dated October 16,2019 and other filings with the SEC and/or The Stock Exchange of Hong Kong Limited that the Company made or makes fr

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1. **公司定位**:Ascentage Pharma为全球商业化阶段血液肿瘤公司,拥有两款创新商业化产品(Olverembatinib、Lisaftoclax)及10+在研管线,双上市(纳斯达克/港交所)。 2. **核心产品**: - **Olverembatinib**(三代BCR-ABL抑制剂):中国获批CML-CP,全球4项III期试验(FDA/EMA cleared),T315I突变疗效显著(CML-CP患者CCyR 60.8%)。 - **Lisaftoclax**(高选择性Bcl-2抑制剂):中国获批CLL/SLL,全球5项III期试验(FDA/EMA cleared),BTKi难治CLL患者ORR 62.5%。 3. **研发进展**: - 13项全球注册性试验(4项FDA III期),40+临床 trials,100+出版物。 - 新管线包括BTK降解剂APG-3288(全球I期)、EED抑制剂APG-5918(贫血/肿瘤)。 4. **财务与团队**:现金储备约4.2亿美元(2025H1),全球团队约800人,478项专利。
癌症新药有哪些? 血液病疗法进展? 全球抗癌突破?
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