您的当前位置：首页 > 行业数据 > 国内阿尔茨海默管线2026年进展预期

国内阿尔茨海默管线2026年进展预期

行业数据

下载图片

原图定位

同报告图片

/ 4

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

<table>
    <thead>
        <tr>
            ```html
<th>药物名称</th>
            <th>研发机构(类型)</th>
            <th>作用机制</th>
            <th>全球最高研发阶段开始日期</th>
            <th>全球最高研发阶段</th>
            <th>中国最高研发阶段</th>
            <th>中国最高研发阶段开始日期</th>
        </tr>
    </thead>
    <tbody>
        <tr>
            <td>17878000048</td>
            <td>绿叶制药(原研)</td>
            <td>TAAR1激动剂;5-HT2C receptor激动剂</td>
            <td>2026-01-15</td>
            <td>II期临床</td>
            <td>II期临床</td>
            <td>2026-01-15</td>
        </tr>
        <tr>
            <td>LPM526000133</td>
            <td>绿叶制药(原研)</td>
            <td>5-HT2C receptor拮抗剂;5-HT2A receptor反向激动剂</td>
            <td>2025-12-23</td>
            <td>II期临床</td>
            <td>II期临床</td>
            <td>2025-12-23</td>
        </tr>
        <tr>
            <td>尼布林</td>
            <td>安域生物(原研)</td>
            <td>USP11抑制剂</td>
            <td>2025-08-28</td>
            <td>I期临床</td>
            <td>I期临床</td>
            <td>2025-08-28</td>
        </tr>
        <tr>
            <td>FN12</td>
            <td>万邦德制药;上海药物研究所(原研)</td>
            <td>AChE抑制剂</td>
            <td>2025-07-15</td>
            <td>II/III期临床</td>
            <td>II/III期临床</td>
            <td>2025-07-15</td>
        </tr>
        <tr>
            <td>IPG8294</td>
            <td>艾美斐生物(原研)</td>
            <td>CD38抑制剂</td>
            <td>2025-06-17</td>
            <td>I期临床</td>
            <td>I期临床</td>
            <td>2025-06-17</td>
        </tr>
        <tr>
            <td>OAB-14</td>
            <td>新华制药;沈阳药科大学(原研)</td>
            <td>RXR激动剂</td>
            <td>2025-05-20</td>
            <td>II期临床</td>
            <td>II期临床</td>
            <td>2025-05-20</td>
        </tr>
        <tr>
            <td>BHV-8000</td>
            <td>高光制药(原研);Biohaven</td>
            <td>JAK1抑制剂;TYK2抑制剂</td>
            <td>2025-05-16</td>
            <td>II/III期临床</td>
            <td>I期临床</td>
            <td>2025-09-29</td>
        </tr>
        <tr>
            <td>咕诺美林</td>
            <td>Karuna Therapeutics(Top20 MNC);Eli Lilly(Top20 MNC) 原研 无权益 ;Novo Nordisk(Top20 MNC) 原研 无权益</td>
            <td>M4 receptor激动剂;M1 receptor激动剂</td>
            <td>2025-04-22</td>
            <td>III期临床</td>
            <td>III期临床</td>
            <td>2025-06-10</td>
        </tr>
        <tr>
            <td>VHB937</td>
            <td>Novartis(Top20 MNC) 原研</td>
            <td>TREM2稳定剂;anti-TREM2单抗;TREM2激动剂</td>
            <td>2024-10-16</td>
            <td>II期临床</td>
            <td>II期临床</td>
            <td>2024-10-16</td>
        </tr>
        <tr>
            <td>咕诺美林+曲司氯铵</td>
            <td>再鼎医药;Karuna Therapeutics(Top20 MNC) 原研</td>
            <td>M4 receptor激动剂;M1 receptor激动剂;mAChR拮抗剂</td>
            <td>2024-09-26</td>
            <td>批准上市</td>
            <td>批准上市</td>
            <td>2025-12-22</td>
        </tr>
        <tr>
            <td>HZ005</td>
            <td>和泽医药(原研)</td>
            <td>D2 receptor激动剂;nAChR拮抗剂;NMDA receptor拮抗剂;5-HT3 receptor拮抗剂</td>
            <td>2024-09-25</td>
            <td>I期临床</td>
            <td>I期临床</td>
            <td>2024-09-25</td>
        </tr>
        <tr>
            <td>八氢氨吖啶</td>
            <td>华洋高科(原研)</td>
            <td>AChE抑制剂;BuChE抑制剂</td>
            <td>2024-08-29</td>
            <td>申请上市</td>
            <td>申请上市</td>
            <td>2024-08-29</td>
        </tr>
        <tr>
            <td>苯加兰他敏</td>
            <td>康哲药业;Alpha Cognition 原研</td>
            <td>cholinesterase抑制剂</td>
            <td>2024-07-26</td>
            <td>批准上市</td>
            <td>申请上市</td>
            <td>2025-07-28</td>
        </tr>
        <tr>
            <td>氢甲硫董</td>
            <td>TauRx Pharmaceuticals 原研</td>
            <td>Tau聚集抑制剂</td>
            <td>2024-07-01</td>
            <td>申请上市</td>
            <td>III期临床</td>
            <td>2025-01-13</td>
        </tr>
        <tr>
            <td>HS-10380</td>
            <td>翰森制药(原研)</td>
            <td>D2 receptor激动剂;5-HT1A receptor激动剂;5-HT2A receptor拮抗剂;D3 receptor激动剂</td>
            <td>2024-04-19</td>
            <td>II期临床</td>
            <td>II期临床</td>
            <td>2024-04-19</td>
        </tr>
        <tr>
            <td>多奈哌齐口腔速溶膜</td>
            <td>力品药业(原研)</td>
            <td>AChE抑制剂;σ1 receptor激动剂;α7 receptor调节剂;α4β2 receptor调节剂</td>
            <td>2023-09-22</td>
            <td>申请上市</td>
            <td>申请上市</td>
            <td>2023-09-22</td>
        </tr>
        <tr>
            <td>BrAD-R13</td>
            <td>博芮健(原研)</td>
            <td>TrkB激活剂</td>
            <td>2023-09-05</td>
            <td>I期临床</td>
            <td>I期临床</td>
            <td>2023-09-05</td>
        </tr>
        <tr>
            <td>JK-50561</td>
            <td>卓凯生物(原研)</td>
            <td>RAC1抑制剂</td>
            <td>2023-01-16</td>
            <td>II期临床</td>
            <td>II期临床</td>
            <td>2023-01-16</td>
        </tr>
        <tr>
            <td>美金刚硝酸酯</td>
            <td>喜鹊医药(原研);暨南大学</td>
            <td>NMDA receptor拮抗剂</td>
            <td>2021-11-10</td>
            <td>II期临床</td>
            <td>II期临床</td>
            <td>2021-11-10</td>
        </tr>
        <tr>
            <td>LY30410</td>
            <td>Insud Pharma;Zambon;Towa Pharmaceutical;绿叶制药(原研);金赛药业;Italfarmaco;Esteve;Myung In Pharm</td>
            <td>AChE抑制剂;BuChE抑制剂</td>
            <td>2021-05-21</td>
            <td>批准上市</td>
            <td>批准上市</td>
            <td>2023-10-27</td>
        </tr>
        <tr>
            <td>Rybelsus</td>
            <td>Emisphere Technologies(Top20 MNC) 原研</td>
            <td>GLP-1R激动剂</td>
            <td>2019-09-20</td>
            <td>批准上市</td>
            <td>批准上市</td>
            <td>2024-01-23</td>
        </tr>
        <tr>
            <td>注射用双羟萘酸多奈哌齐</td>
            <td>华汇拓(原研)</td>
            <td>AChE抑制剂;σ1 receptor激动剂;α7 receptor调节剂;α4β2 receptor调节剂</td>
            <td>2019-04-18</td>
            <td>I期临床</td>
            <td>I期临床</td>
            <td>2019-04-18</td>
        </tr>
        <tr>
            <td>司美格鲁肽</td>
            <td>Novo Nordisk(Top20 MNC) 原研</td>
            <td>GLP-1R激动剂</td>
            <td>2017-12-05</td>
            <td>批准上市</td>
            <td>批准上市</td>
            <td>2021-04-27</td>
        </tr>
        <tr>
            <td>美可比林</td>
            <td>欧威医药;益诺依;江苏先声医药集团(原研);宁丹新药</td>
            <td>AChE抑制剂;NA;TRPML1抑制剂;calcium channel阻断剂</td>
            <td>2017-11-23</td>
            <td>I期临床</td>
            <td>I期临床</td>
            <td>2017-11-23</td>
        </tr>
        <tr>
            <td>萝卜硫素</td>
            <td>Evgen Pharma 原研 ;Stalicla</td>
            <td>HDAC抑制剂</td>
            <td>2016-01-13</td>
            <td>III期临床</td>
            <td>III期临床</td>
            <td>2019-04-30</td>
        </tr>
        <tr>
            <td>布瑞哌唑</td>
            <td>Otsuka 原研 ;Lundbeck</td>
            <td>5-HT1A receptor部分激动剂;D2 receptor部分激动剂;5-HT2A receptor拮抗剂</td>
            <td>2015-07-10</td>
            <td>批准上市</td>
            <td>批准上市</td>
            <td>2024-06-25</td>
        </tr>
        <tr>
            <td>varoglutamstat</td>
            <td>Vivoryon Therapeutics 原研 ;江苏先声医药集团</td>
            <td>QPCT抑制剂;QPCTL抑制剂</td>
            <td>2015-03-17</td>
            <td>II期临床</td>
            <td>II期临床</td>
            <td>2022-03-02</td>
        </tr>
        <tr>
            <td>多奈哌齐+美金刚</td>
            <td>Forest Laboratories(Top20 MNC)(原研)</td>
            <td>AChE抑制剂;D2 receptor激动剂;σ1 receptor激动剂;α7 receptor调节剂;nAChR拮抗剂;NMDA receptor拮抗剂;α4β2 receptor调节剂;5-HT3 receptor拮抗剂</td>
            <td>2014-12-23</td>
            <td>批准上市</td>
            <td>申请上市</td>
            <td>2022-10-24</td>
        </tr>
        <tr>
            <td>Exelon Patch</td>
            <td>Novartis(Top20 MNC) 原研</td>
            <td>AChE抑制剂;BuChE抑制剂</td>
            <td>2007-07-06</td>
            <td>批准上市</td>
            <td>批准上市</td>
            <td>2017-11-21</td>
        </tr>
        <tr>
            <td>瑞舒伐他汀</td>
            <td>AstraZeneca(Top20 MNC);Shionogi 原研 ;Grünenthal</td>
            <td>HMG-CoA reductase抑制剂</td>
            <td>2003-03-07</td>
            <td>批准上市</td>
            <td>批准上市</td>
            <td>2006-11-29</td>
        </tr>
        <tr>
            <td>曲司氯铵</td>
            <td>Madaus;Allergan(Top20 MNC);Indevus Pharmaceuticals 原研</td>
            <td>mAChR拮抗剂</td>
            <td>2000-05-04</td>
            <td>批准上市</td>
            <td>批准上市</td>
            <td>2004-10-29</td>
        </tr>
        <tr>
            <td>石杉碱甲</td>
            <td>太龙药业(原研)</td>
            <td>AChE抑制剂</td>
            <td>1994-01-01</td>
            <td>批准上市</td>
            <td>批准上市</td>
            <td>1994-01-01</td>
        </tr>
        <tr>
            <td>氯噻嗪</td>
            <td>Merck & Co.(Top20 MNC) 原研</td>
            <td>NCC抑制剂</td>
            <td>1958-09-04</td>
            <td>批准上市</td>
            <td>I期临床</td>
            <td>2015-07-19</td>
        </tr>
        <tr>
            <td>米罗那非</td>
            <td>Acino;SK Chemicals 原研 ;复星医药;AriBio;纽科智联(无权益)</td>
            <td>PDE5抑制剂</td>
            <td></td>
            <td>批准上市</td>
            <td>III期临床</td>
            <td>2022-09-08</td>
        </tr>
    </tbody>
</table>

资料来源：医药魔方，中泰证券研究所
```

所属报告：

医药生物行业专题报告：2026阿尔茨海默（AD）投资日历-260308（15页）.pdf

打包全文图表

争”的特点。从赛神医药的大额 BD，到绿叶制药在 ADP 领域的临床推进，表明中国药企正在全球 AD 研发版图中扮演越来越多元和重要的角色。 ◼ 合作与出海成为亮点：赛神医药与诺华高达 16.65 亿美元的合作是 2026 年初中国 AD 领域最重磅的事件，标志着中国源头创新在神经退行性疾病领域获得国际巨头认可。绿叶制药 LY03017 快速获得美国 FDA 临床许可也体现了其全球化开发策略。差异化赛道受关注：中国药企在 AD 领域并非单纯跟随 Aβ靶点，在神经保护和全新信号通路上的探索正走向前台。深圳理工大学 / 博芮健 (BrAD-R13)差异化点是全球首款口服 TrkB 受体激动剂。2025 年 9 月已完成 I 期临床，计划在 2026 年内在中国和美国启动多中心临床试验，该药不仅能抑制致病蛋白产生，还能通过激活 BDNF-TrkB 信号通路发挥神经保护作用，实现“疾病修饰”目标。它是目前全球少有的能够口服且高效率穿透血脑屏障的此类靶点药物。临床数据密集读出：2026年国内 AD 临床研发管线将迎来多个关键数据读出节点。新华制药 OAB-14的 II 期数据以及万邦德石杉碱甲控释片的大规模 II/III 期试验进展是关注焦点。再鼎医药 (KarXT)：重点关注其治疗 AD 精神病的全球 III 期数据（ADEPT-2）在 2026 年底前的公布。商业化与生态构建：北京协和医院发布的仑卡奈单抗真实世界数据，有助于推动这类疾病修饰疗法在中国的规范应用和市场教育。早期管线与平台技术：康诺亚的 KeyCND™ (BBB-XOC) 穿梭机平台是其核心竞争力。通过双抗或多抗技术提高抗体在脑内的生物利用度，意味着可以用更低的全身给药剂量达到同等的脑内药效，从而显著降低 ARIA（脑水肿/出血）的风险。该过脑平台有望作为“底层架构”授权给全球药企或用于后续管线，具有极强的平台扩展性。康诺亚布局的 siRNA 管线旨在实现“长效管理”。迈威生物针对阿尔茨海默病（AD）研发了 Aβ抗体 MWTX-4611，临床前数据显示优于标杆药物仑卡奈单抗的寡聚体选择性和进脑率。

行业数据原图定位