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BGB-445呈现剂量依赖性疗效变化
BGB-445呈现剂量依赖性疗效变化
行业数据
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图片格式：PNG
图片大小：642KB
图片尺寸：2280*1047
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所属报告：
百济神州-公司研究报告-百创新药蛟龙出海浪滔滔-230522（68页）.pdf
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行业数据
2025-09-05
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BGB-43395的剂量爬坡和优化临床设计以及安全性数据
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行业数据
2025-08-08
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R/RCLL最新PFS数据支持BGB-16673开展与匹妥布替尼的头对头试验
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行业数据
2025-08-07
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BGB-43395安全性数据
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行业数据
2025-08-07
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BTKi及BCL2i经治的后线CLL/SLL临床数据（非头对头对比）：BGB-16673初步展现治疗优势
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2025-08-07
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表11、BGB-16673与非共价BTK或其他BTKPROTAC在治疗R/RCLL/SLL的临床数据对比（非头
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2025-07-24
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表7、BGB-43395与CDK4、CDK4/6抑制剂在治疗2L+ER+乳腺癌的临床数据对比（非头对头对比）
fCDoja/niakgfCBCR0ItNDMzOTUgfCBhYmVtYWNpY2xpYiB8IOWTjOafj+ilv+WIqSB8IOeRnuazouilv+WIqSB8IOmYv+i0neilv+WIqSB8CnwgLS0tIHwgLS0tIHwgLS0tIHwgLS0tIHwgLS0tIHwgLS0tIHwKfCDlhazlj7ggfCDnmb7mtY7npZ7lt54gfCDovonnkZ4gfCDovonnkZ4v5a6J6L+bIHwg6K+65Y2OIHwg56S85p2lIHwKfCDkvZznlKjmnLrliLYgfCBDREs0IHwgQ0RLNCB8IENESzQvNiB8IENESzQvNiB8IENESzQvNiB8Cnwg5Li05bqK566A56ewIHwgTkNUMDYxMjAyODMgfCBOQ1QwNDU1NzQ0OSB8IFBBTE9NQS0zIHwgTU9OQUxFRVNBLTMgfCBwb3N0TU9OQVJDSCB8Cnwg5Li05bqK6Zi25q61IHwgMeacnyB8IDEvMuacnyB8IDPmnJ8gfCAz5pyfIHwgM+acnyB8Cnwg5oKj6ICF5Z+657q/IHwg5Lit5L2NNEznu4/msrvvvJs5MyXkubPohbrnmYzmgqPogIXnu4/ov4dDREs0LzbmsrvnlpcgfCDkuK3kvY00TOe7j+ayu++8m+Wdh+e7j+i/h0NESzQvNuayu+eWlyB8IDFM57uP5rK75oiWMUwr57uP5rK7IHwgMUznu4/msrvmiJbliJ3msrsgfCAxTOe7j+ayu++8m+Wdh+e7j+i/h0NESzQvNuayu+eWlyB8Cnwg5Y+X6K+V5Lq65pWwIHwg6IGU55So5rCf57u05Y+4576k5YmC6YeP6YCS5aKe77yb5Lmz6IW655mMbj0yOSB8IOiBlOeUqOWGheWIhuazjOayu+eWl++8m249MzMgfCDogZTnlKjmsJ/nu7Tlj7jnvqRuPTM0N++8m+WuieaFsOWJguiBlOeUqOawn+e7tOWPuOe+pG49MTc0IHwg6IGU55So5rCf57u05Y+4576kbj00ODTvvJvlronmhbDliYLogZTnlKjmsJ/nu7Tlj7jnvqRuPTI0MiB8IOiBlOeUqOawn+e7tOWPuOe+pG49MTgy77yb5a6J5oWw5YmC6IGU55So5rCf57u05Y+4576kbj0xODYgfAp8IG1QRlMgfCAvIHwgOC4x5Liq5pyIIHwgOS415Liq5pyI77yIdnPlronmhbDliYLnu4Q0LjbkuKrmnIjvvIkgfCAyMC415Liq5pyI77yIdnPlronmhbDliYLnu4QxMi445Liq5pyI77yJIHwgNi4w5Liq5pyI77yIdnPlronmhbDliYLnu4Q1LjPkuKrmnIjvvIkgfAp8IE9SUiB8IDExJe+8iDIvMTnvvIkgfCAzMiXvvIg4LzI177yJIHwgMTkl77yIdnPlronmhbDliYLnu4Q5Je+8iSB8IDMyJe+8iHZz5a6J5oWw5YmC57uEMjIl77yJIHwgMTYuOCXvvIh2c+WuieaFsOWJgue7hDcuMSXvvIkgfAp8IENSL0NSaSB8IC8gfCA0LjAl77yIMS8yNe+8iSB8IDDvvIh2c+WuieaFsOWJgue7hDIl77yJIHwgMS43Je+8iHZz5a6J5oWw5YmC57uEMCXvvIkgfCAwLjgl77yIdnPlronmhbDliYLnu4QxLjYl77yJIHwKfCBURUFFIHwgRzMr5Lit5oCn57KS5YeP5bCR77yaMTYuMiUgfCBHMyvkuK3mgKfnspLlh4/lsJHvvJoxOC4yJSB8IEczK+S4reaAp+eykuWHj+Wwke+8mjY1Je+8iHZz5a6J5oWw5YmC57uEMSXvvIkgfCBHMy805Lit5oCn57KS5YeP5bCR77yaNTMl77yIdnPlronmhbDliYLnu4QwJe+8iSB8IEczK+S4reaAp+eykuWHj+Wwke+8mjU1Je+8iHZz5a6J5oWw5YmC57uEMCXvvIkgfAoK6LWE5paZ5p2l5rqQ77ya5YWs5Y+4MjAyNeW5tOeglOWPkeaXpeWxleekuuadkOaWme+8m1RpbW90aHkgWWFwLCBldCBhbC4sIEZpcnN0LWluLWh1bWFuIHBoYXNlIEkvSUlhIHN0dWR5IG9mIHRoZQ==
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2025-07-24
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图20、BGB-45035针对IRAK4降解的临床前数据
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2025-05-23
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广泛期小细胞肺癌占比约75%，往往依赖系统性治疗，预后整体较差
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2025-05-13
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BGB-16673有望成为潜在同类最佳降解剂
fCDml6LlvoDmsrvnlpfnur/mlbDkuK3kvY3mlbAgfCA0IHwgMyB8CnwtLS0tLS0tLS0tLS0tLS0tLS0tLS0tfC0tLS0tLXwtLS0tLS18CnwgQlRL5oqR5Yi25YmCK0JDTDLmipHliLbliYLmmrTpnLIgfCA2MyUgIHwgNTAlICB8Cnwg5Zug55a+55eF6L+b5bGV5a+86Ie05pei5b6AQlRL5oqR5Yi25YmC5rK755aX57uI5q2iIHwgODklICB8IDcxJSAgfA==
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2025-04-18
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