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低水平Trop2mRNA与ER-BC生存率升高相
低水平Trop2mRNA与ER-BC生存率升高相
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医药生物行业：TROP2 ADC行业专题-241226（26页）.pdf
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（1）乳腺癌(BC)：Trop2和肿瘤细胞的侵袭和转移高度相关，但BC的发生还取决于Trop2的激活状态及定位，数据表明，膜定位的Trop2可能是不良的预后因素，而胞内定位的Trop2可能与良好的预后相关。此外，Trop2的预后价值也与雌激素受体（ER）的状态有关。低水平的Trop2 mRNA与ER阳性BC的生存率降低相关，但与ER阴性BC的生存率增加相关。
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医药生物行业：TROP2 ADC行业专题-241226（26页）.pdf
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