1、K UNITED STATESSECURITIES AND EXCHANGE COMMISSIONWashington,D.C.20549 Form 10-K(Mark One)ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d)OF THE SECURITIES EXCHANGE ACT OF 1934For the fiscal year ended December 31,2018 OrTRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d)OF THE SECURITIES EXCHANGE ACT OF
2、1934For the transition period from to Commission File Number 001-34899 Pacific Biosciences of California,Inc.(Exact name of registrant as specified in its charter)Delaware16-1590339(State or other jurisdiction ofincorporation or organization)(I.R.S.EmployerIdentification No.)1305 OBrien DriveMenlo P
3、ark,CA 9402594025(Address of principal executive offices)(Zip Code)(Registrants telephone number,including area code)(650)521-8000Securities registered pursuant to Section 12(b)of the Act:Title of Each Class Name of Each Exchange on Which Registered Common Stock,par value$0.001 per shareThe NASDAQ S
4、tock Market LLCSecurities registered pursuant to Section 12(g)of the Act:None Indicate by check mark if the registrant is a well-known,seasoned issuer,as defined in Rule 405 of the Securities Act.Yes No Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 o
5、r Section 15(d)of the Act.Yes No Indicate by check mark whether the registrant(1)has filed all reports required to be filed by Section 13 or 15(d)of the Securities Exchange Act of 1934during the preceding 12 months(or for such shorter period that the registrant was required to file such reports),and
6、(2)has been subject to such filingrequirements for the past 90 days.Yes No Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 ofRegulation S-T(232.405 of this chapter)during the preceding 12 months(or f