1、NoImageNoImage2026 J.P.Morgan Healthcare ConferenceRand Sutherland,MD,Chief Executive OfficerJanuary 2026 2026 Upstream Bio,Inc.NoImageNoImageNoImageNoImageThis presentation contains forward-looking statements of Upstream Bio,Inc.(“Upstream,”“the Company,”“we,”“us,”or“our”)that involve substantial r
2、isks and uncertainties.All statements other than statements of historical facts contained in this presentation,including statements regarding our future financial condition,results of operations,business strategy and plans,and objectives of management for future operations,as well as statements rega
3、rding industry trends,are forward-looking statements.In some cases,you can identify forward-looking statements by terminology such as“anticipate,”“believe,”“continue,”“could,”“estimate,”“expect,”“intend,”“may,”“plan,”“potentially”“predict,”“should,”“will”or the negative of these terms or other simil
4、ar expressions.We have based these forward-looking statements largely on our current expectations and projections about future events and trends that we believe may affect our financial condition,results of operations,business strategy and financial needs.These forward-looking statements are subject
5、 to a number of risks,uncertainties and assumptions,including,among other things:the initiation,timing,progress,and results of our planned and future clinical trials for verekitug,including our clinical trials in severe asthma,chronic rhinosinusitis with nasal polyps,and chronic obstructive pulmonar
6、y disease;our ability to replicate positive results from earlier preclinical studies or clinical trials conducted by us or third parties in current or future clinical trials;our ability to demonstrate that verekitug and any potential future product candidates are safe and effective for their propose