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诺为泰(Novotech):2023血脂异常:全球临床试验概况报告(中译版)(19页).pdf

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1、novotech-OCTOBER 5,2023Dyslipidaemia Global Clinical trial landscape(2023)WHO 2008 estimates indicate that Europe and America have higher hypercholesterolemia rates than Southeast Asia and AfricaIn the Asia Pacific regions,Japan had a relatively elevated prevalence of high total cholesterol(TC)Malay

2、sia reported a notably high TC prevalence between 2006 and 2012The Philippines had alarmingly high TC and low HDL-C levels in 2013,emphasizing the necessity for region-specific strategies to tackle lipid-related health concernsAPAC contributed 65%of Dyslipidaemia trials,notably driven by Mainland Ch

3、ina and South KoreaUS and Europe conducted 30%of Dyslipidaemia trials;the US led in North America,UK in EuropeAPAC has not only demonstrated considerably shorter recruitment durations but has also shown notably faster patient recruitment ratesEurope led with substantial progress and favourable resea

4、rch,while APAC and North America progressed steadily but more slowlyDYSLIPIDAEMIAGLOBAL CLINICAL TRIAL LANDSCAPE The content of this publication is proprietary to Novotech Health Holdings.No part of this publication may be reproduced,distributed,or transmitted in any form or by any means,including p

5、hotocopying,recording,or other electronic or mechanical methods,without the prior written permission of Novotech except in the case of quotations embodied in reviews and non-commercial uses.Please note that this copyright statement applies specifically to this publication and its content and does no

6、t extend to other materials or intellectual property owned by Novotech.Any unauthorized reproduction or distribution of this publication or any portion thereof may result in legal action taken by Novotech to protect its rights.For permissions or inquiries,please contact:communicationsnovotech-Dyslip

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本文主要介绍了全球脂质异常(即血脂异常)的流行病学、标准治疗、临床试验景观、关键意见领袖以及Novotech公司的概况。 1. 流行病学:根据世界卫生组织2008年的估计,欧洲和美洲的高胆固醇血症率高于东南亚和非洲。亚太地区,日本相对较高,马来西亚在2006-2012年间报告了显著的高胆固醇水平。菲律宾在2013年有惊人的高胆固醇和低HDL-C水平。 2. 标准治疗:生活方式改变是治疗血脂异常的第一步,包括饮食和锻炼。一线治疗是抑制HMG-CoA还原酶的药物,如他汀类药物。 3. 临床试验景观:自2018年以来,全球生物制药行业启动了超过500项血脂异常临床试验,其中65%发生在亚太地区。中国和大韩民国成为该地区的重点。美国和欧洲也进行了近30%的试验。 4. 关键意见领袖:文章列出了几位在血脂异常领域有影响力的专家,包括来自中国、台湾、澳大利亚、印度和美国的研究人员。 5. Novotech公司:Novotech是一家总部位于亚太地区的生物制药合同研究组织,具有全球执行能力。它为在亚太、美国和欧洲进行临床试验的生物技术客户提供服务。
亚太地区高胆固醇患病率为何如此之高? 目前治疗高血脂症的标准治疗方法是什么? 哪些药物正在研发中,用于治疗高血脂症?
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