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1、Unlocking Better Futures,Delivering Next-Level ValueBrett P.Monia,Ph.D.,Chief Executive Officer JP Morgan Healthcare Conference|January 2024|Nasdaq:IONSForward-Looking StatementsThis presentation includes forward-looking statements regarding our business,financial guidance and the therapeutic and co
2、mmercialpotential of our commercial medicines,additional medicines in development and technologies.Any statement describing Ionis goals,expectations,financial or other projections,intentions or beliefs is a forward-looking statement and should be considered an at-riskstatement.Such statements are su
3、bject to certain risks and uncertainties including but not limited to those related to our commercialproducts and the medicines in our pipeline,and particularly those inherent in the process of discovering,developing andcommercializing medicines that are safe and effective for use as human therapeut
4、ics,and in the endeavor of building a businessaround such medicines.Ionis forward-looking statements also involve assumptions that,if they never materialize or prove correct,could cause its results to differ materially from those expressed or implied by such forward-looking statements.Although Ionis
5、 forward-looking statements reflect the good faith judgment of its management,these statements are based only on facts and factors currentlyknown by Ionis.As a result,you are cautioned not to rely on these forward-looking statements.These and other risks concerning Ionisprograms are described in add
6、itional detail in Ionis annual report on our Form 10-K for the year ended December 31,2022,and ourmost recent Form 10-Q quarterly filing,which are on file with the SEC.Copies of these and other documents are available .In this presentation,unless the context requires otherwise,“Ionis,”“Company,”“we,